Search Our Scientific Publications & Authors

Publications
find publications by category +
Translate page:

First Prototype of the Infectious Diseases Seeker (IDS) Software for Prompt Identification of Infectious Diseases.

Authors:
F Baldassi O Cenciarelli A Malizia P Gaudio

J Epidemiol Glob Health 2020 12 21;10(4):367-377. Epub 2020 Jul 21.

Department of Industrial Engineering, University of Rome Tor Vergata, Rome, Italy.

The rapid detection of ongoing outbreak - and the identification of causative pathogen - is pivotal for the early recognition of public health threats. The emergence and re-emergence of infectious diseases are linked to several determinants, both human factors - such as population density, travel, and trade - and ecological factors - like climate change and agricultural practices. Several technologies are available for the rapid molecular identification of pathogens [e.g. real-time polymerase chain reaction (PCR)], and together with on line monitoring tools of infectious disease activity and behaviour, they contribute to the surveillance system for infectious diseases. Web-based surveillance tools, infectious diseases modelling and epidemic intelligence methods represent crucial components for timely outbreak detection and rapid risk assessment. The study aims to integrate the current prevention and control system with a prediction tool for infectious diseases, based on regression analysis, to support decision makers, health care workers, and first responders to quickly and properly recognise an outbreak. This study has the intention to develop an infectious disease regressive prediction tool working with an off-line database built with specific epidemiological parameters of a set of infectious diseases of high consequences. The tool has been developed as a first prototype of a software solution called Infectious Diseases Seeker (IDS) and it had been established in two main steps, the database building stage and the software implementation stage (MATLAB environment). The IDS has been tested with the epidemiological data of three outbreaks occurred recently: severe acute respiratory syndrome epidemic in China (2002-2003), plague outbreak in Madagascar (2017) and the Ebola virus disease outbreak in the Democratic Republic of Congo (2018). The outcomes are promising and they reveal that the software has been able to recognize and characterize these outbreaks. The future perspective about this software regards the developing of that tool as a useful and user-friendly predictive tool appropriate for first responders, health care workers, and public health decision makers to help them in predicting, assessing and contrasting outbreaks.

Download full-text PDF

 Source
http://dx.doi.org/10.2991/jegh.k.200714.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758858PMC
December 2020

Publication Analysis

Top Keywords

infectious diseases
32
infectious
9
prediction tool
8
tools infectious
8
public health
8
decision makers
8
health care
8
seeker ids
8
care workers
8
diseases seeker
8
infectious disease
8
diseases
8
outbreak
5
tool
5
software
5
timely outbreak
4
outbreak detection
4
crucial components
4
components timely
4
environment ids
4

Keyword Occurance

Similar Publications

Consensus statement on blocking interleukin-6 receptor and interleukin-6 in inflammatory conditions: an update.

Authors:
Daniel Aletaha Andreas Kerschbaumer Kastriot Kastrati Christian Dejaco Maxime Dougados Iain B McInnes Naveed Sattar Tanja A Stamm Tsutomu Takeuchi Michael Trauner Désirée van der Heijde Marieke Voshaar Kevin L Winthrop Angelo Ravelli Neil Betteridge Gerd-Rüdiger R Burmester Johannes Wj Bijlsma Vivian Bykerk Roberto Caporali Ernest H Choy Catalin Codreanu Bernard Combe Mary K Crow Maarten de Wit Paul Emery Roy M Fleischmann Cem Gabay Merete Lund Hetland Kimme L Hyrich Annamaria Iagnocco

Ann Rheum Dis 2022 Aug 11. Epub 2022 Aug 11.

Scienze Cliniche e Biologiche, Università degli Studi di Torino, Torino, Italy.

Background: Targeting interleukin (IL)-6 has become a major therapeutic strategy in the treatment of immune-mediated inflammatory disease. Interference with the IL-6 pathway can be directed at the specific receptor using anti-IL-6Rα antibodies or by directly inhibiting the IL-6 cytokine. This paper is an update of a previous consensus document, based on most recent evidence and expert opinion, that aims to inform on the medical use of interfering with the IL-6 pathway. Read More

View Article and Full-Text PDF
August 2022
Similar Publications

Global monitoring of public interest in preventive measures against COVID-19 via analysis of Google Trends: an infodemiology and infoveillance study.

Authors:
Tomoo Ito

BMJ Open 2022 Aug 11;12(8):e060715. Epub 2022 Aug 11.

Bureau of International Health Cooperation, National Center for Global Health and Medicine, Shinjuku-ku, Tokyo, Japan

Objectives: The COVID-19 pandemic has influenced people's concerns regarding infectious diseases and their preventive measures. However, the magnitude of the impact and the difference between countries are unclear. This study aimed to assess the magnitude of the impact of COVID-19 on public interest and people's behaviours globally in preventing infectious diseases while comparing international trends and sustainability. Read More

View Article and Full-Text PDF
August 2022
Similar Publications

Diagnostic accuracy of urinary antigen tests for pneumococcal pneumonia among patients with acute respiratory failure suspected pneumonia: a systematic review and meta-analysis.

Authors:
Shunsuke Yasuo Maki Murata Natsuki Nakagawa Takeshi Kawasaki Takuo Yoshida Koichi Ando Satoshi Okamori Yohei Okada

BMJ Open 2022 Aug 11;12(8):e057216. Epub 2022 Aug 11.

Department of Primary Care and Emergency Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Kyoto, Japan.

Background/objectives: Urinary antigen tests have been used for the rapid identification of infection in patients with pneumonia, thereby leading to earlier targeted therapy than when using conventional diagnostic culture methods. This study aimed to update the knowledge on the diagnostic accuracy of urinary antigen tests for among patients with acute respiratory failure suspected of pneumonia based on a systematic review and meta-analysis.

Methods: A systematic search was performed using MEDLINE and the Cochrane Central Register of Controlled Trials for studies published up to 3 June 2020. Read More

View Article and Full-Text PDF
August 2022
Similar Publications

Infectious Pulmonary Diseases.

Authors:
Rachel Rafeq Lauren A Igneri

Emerg Med Clin North Am 2022 Aug 9;40(3):503-518. Epub 2022 Jul 9.

Critical Care, Department of Pharmacy, Cooper University Healthcare, 1 Cooper Plaza, Camden, NJ 08103, USA.

Pneumonia is a lower respiratory tract infection caused by the inability to clear pathogens from the lower airway and alveoli. Cytokines and local inflammatory markers are released, causing further damage to the lungs through the accumulation of white blood cells and fluid congestion, leading to pus in the parenchyma. The Infectious Diseases Society of America defines pneumonia as the presence of new lung infiltrate with other clinical evidence supporting infection, including new fever, purulent sputum, leukocytosis, and decline in oxygenation. Read More

View Article and Full-Text PDF
August 2022
Similar Publications

SARS-CoV-2 remains infectious for at least a month on artificially-contaminated frozen berries.

Authors:
Malak A Esseili Amy Mann Revati Narwankar Issmat I Kassem Francisco Diez-Gonzalez Robert J Hogan

Food Microbiol 2022 Oct 21;107:104084. Epub 2022 Jun 21.

Animal Health Research Center, Department of Biomedical Sciences and Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, GA 30223, USA.

The potential transmission of SARS-CoV-2 via food has been controversial since the beginning of the COVID-19 pandemic. To investigate these concerns, reliable detection methods and data on virus die-off rates in various foods are needed. Here, an FDA-standard method for the detection of enteric viruses' RNA from soft fruits was modified for the recovery of infectious SARS-CoV-2. Read More

View Article and Full-Text PDF
October 2022
Similar Publications
}