Acta Myol 2020 Jun 1;39(2):57-66. Epub 2020 Jun 1.
Dino Ferrari Centre, Department of Pathophysiology and Transplantation (DEPT), Neuroscience Section, University of Milan, Italy.
Oncologist 2021 Mar 3. Epub 2021 Mar 3.
Division of Hematology and Oncology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA.
Background: The aim of this study was to characterize severe irAEs seen among hospitalized patients and to examine risk factors for irAE admissions and clinically relevant outcomes, including length of stay, ICI discontinuation, readmission, and death.Methods: Patients who received ICI therapy (ipilimumab, pembrolizumab, nivolumab, atezolizumab, durvalumab, avelumab, or any ICI combination) at Massachusetts General Hospital (MGH) and were hospitalized at MGH following ICI initiation between January 1, 2011 and October 24, 2018 were identified using pharmacy and hospital admission databases. Medical records of all irAE admissions were reviewed and specialist review with defined criteria was performed. Read More
Brain Behav 2021 Mar 2:e02073. Epub 2021 Mar 2.
Department of Neurology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Background: Benign monomelic amyotrophy of lower limb (BMALL) is a neurogenic syndrome representing an unclear field. Further studies might be helpful to elucidate uncertainties regarding causation, outcome, and the risk of progression to amyotrophic lateral sclerosis (ALS).Methods: According to the inclusion and exclusion criteria, 37 patients with BMALL were retrospectively collected in three neuromuscular centers from January 2012 to October 2018. Read More
Autophagy 2021 Feb 8:1-382. Epub 2021 Feb 8.
Hong Kong Baptist University, School of Chinese Medicine, Hong Kong, China.
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Read More
Amyotroph Lateral Scler Frontotemporal Degener 2021 Feb 12:1-3. Epub 2021 Feb 12.
Centre de référence SLA, CHU Montpellier, Univ Montpellier, INSERM, Montpellier, France.
Covid-19-related lockdown (LD) in France precluded in-person follow-up in referral ALS centers. ALS patients' evolution and worsening before and during LD were studied to analyze its impact. A total of 84 patients were identified. Read More
Neurology 2021 Feb 10. Epub 2021 Feb 10.
Referral Center for Neuromuscular Diseases and ALS, Timone University Hospital, Aix-Marseille University, Marseille, France.
Objective: To describe the clinical characteristics and outcomes of COVID-19 among patients with MG and identify factors associated with COVID-19 severity in MG patients.Methods: The CO-MY-COVID registry was a multicenter, retrospective, observational cohort study conducted in neuromuscular referral centers and general hospitals of the FILNEMUS network (between March 1, 2020, and June 8, 2020), including MG patients with a confirmed or highly-suspected diagnosis of COVID-19. COVID-19 was diagnosed based on a polymerase chain reaction (PCR) test from a nasopharyngeal swab and/or SARS-CoV-2 serology, thoracic computed tomography (CT-scan), or typical symptoms. Read More