Turk J Haematol 2020 Nov 16;37(4):286-287. Epub 2020 Jun 16.
University of Siena, Hematology, Siena, Italy
J Am Vet Med Assoc 2021 May;258(9):999-1006
Case Description: 4 dogs, 7.5 to 10 years of age, were presented for evaluation of signs of chronic cervical pain and forelimb lameness secondary to cervical foraminal intervertebral disk protrusion (IVDP). All dogs were refractory to ≥ 2 weeks of conservative management including strict rest and pain management with anti-inflammatory drugs, methocarbamol, and gabapentin. Read More
Cancer Immunol Res 2021 Apr 14. Epub 2021 Apr 14.
CCR, National Cancer Institute.
This study examined the ability of a papillomavirus-like particle drug-conjugate, belzupacap sarotalocan (AU-011) to eradicate subcutaneous tumors after intravenous injection and to subsequently elicit long-term anti-tumor immunity in the TC-1 syngeneic murine tumor model. Upon in vitro activation with near-infrared light (NIR), AU-011-mediated cell killing was pro-immunogenic in nature, resulting in the release of damage-associated molecular patterns such as DNA, ATP, and HMGB-1, activation of caspase-1, and surface re-localization of calreticulin and HSP70 on killed tumor cells. A single in vivo administration of AU-011 followed by NIR caused rapid cell death, leading to long-term tumor regression in ~50% of all animals. Read More
J Cardiovasc Surg (Torino) 2021 Apr 8. Epub 2021 Apr 8.
University Clinic for Cardiac Surgery, Leipzig Heart Center, Leipzig, Germany.
Background: Patients with tricuspid valve (TV) disease and indication for TV surgery frequently have permanent pacemaker (PM) or defibrillator (AICD) leads, placed in the right ventricle (RV). The aim of this study was to analyse postoperative results and mid-term outcomes after isolated TV surgery (with no further concomitant cardiac procedures) in the presence of permanent RV leads.Methods: From January 2005 to January 2019 a total of 80 patients (mean age: 67. Read More
Int J Dent Hyg 2021 Apr 8. Epub 2021 Apr 8.
Post-Graduation Program in Dentistry, Federal University of Santa Catarina, Florianópolis, Brazil.
Objective: To review the scientific literature and identify dental plaque control strategies focussed on elderly people that improve plaque indices.Design: Scoping review (Joanna Briggs protocol).Data Sources: Individual search strategies developed for six databases. Read More
Case Rep Oncol 2021 Jan-Apr;14(1):365-370. Epub 2021 Mar 8.
Department of Medical Oncology, Cantonal Hospital Baden, Baden, Switzerland.
Small-cell carcinoma of the pancreas (PSCC) is a highly aggressive neoplasia with a dismal prognosis. It is extremely rare, with only a few cases reported in the literature. There is a paucity of clinical data to guide management and since the disease is mainly diagnosed at an advanced stage standard treatment consists of chemotherapy based upon treatment protocols used for small-cell lung cancer. Read More