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Comparing the area under the curve and peak height methods in the calculation of FLT3-ITD allelic ratio.

Authors:
Pietro Di Ciaccio Anabel Kearney Silvia Ling

Int J Lab Hematol 2020 10 13;42(5):e234-e236. Epub 2020 Jun 13.

Department of Haematology, Liverpool Hospital, Sydney, NSW, Australia.

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http://dx.doi.org/10.1111/ijlh.13263DOI Listing
October 2020

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Technical note: multi-alleles at the DYS385ab locus with high frequency in a Han Chinese population from southwestern China.

Authors:
Jiewen Fu Shangyi Fu Shiqiang Yin Jingliang Cheng Xiaoyan Liu Zeming Jin Tao He Junjiang Fu

Int J Legal Med 2021 Apr 12. Epub 2021 Apr 12.

Laboratory of Forensic DNA, the Judicial Authentication Center, Southwest Medical University, Luzhou, 646000, Sichuan, China.

Y-chromosome short tandem repeat (Y-STR) markers have been widely used in forensic applications and usually show monoallelic or diallelic genotypic patterns at certain double-copied loci. In this study, we have found 13 samples among 703 males with multi-alleles at the DYS385ab locus, including one with five mutant alleles, nine with four, and three with three. The frequency of abnormal DYS385ab genotypes was 1. Read More

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April 2021
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How does the side of approach impact the force delivered during external chest compression?

Authors:
Jui-Yi Tsou Chia-Lung Kao Ming-Yuan Hong Chih-Jan Chang Fong-Chin Su Chih-Hsien Chi

Am J Emerg Med 2021 Mar 30;48:67-72. Epub 2021 Mar 30.

Department of Emergency Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan. Electronic address:

Background: We investigated the biomechanics of four external chest compression (ECC) approaches involving different sides of approach and hand placement during cardiopulmonary resuscitation (CPR).

Methods: A total of 60 participants (30 women and 30 men) with CPR certification performed standard continuous 2-min ECC on a Resusci Anne manikin with real-time feedback in four scenarios: rescuer at the manikin's right side with right hand chest contact (RsRc), rescuer at the manikin's right side with left hand chest contact (RsLc), rescuer at the manikin's left side with left hand chest contact (LsLc), and rescuer at the manikin's left side with right hand chest contact (LsRc). Pressure distribution maps of the palm, peak compression pressure, and compression forces were analysed. Read More

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March 2021
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Thrombin generation is associated with ischemic stroke at a young age.

Authors:
Samantha J Donkel Karmen Pater Frank W G Leebeek Diederik W J Dippel Hugo Ten Cate Moniek P M de Maat

Thromb Res 2021 Mar 29;202:139-144. Epub 2021 Mar 29.

Erasmus MC, University Medical Center Rotterdam, Department of Hematology, the Netherlands. Electronic address:

Introduction: Understanding the underlying mechanisms in ischemic stroke (IS) in young adults remains challenging. Thrombin activates processes that contribute to the development and progression of arterial diseases. We investigated the association between thrombin generation (TG) and a first IS or transient ischemic attack (TIA) in young adults. Read More

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March 2021
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Role of a thrombin generation assay in the prediction of infection severity.

Authors:
Boaz Elad Gilat Avraham Naama Schwartz Adi Elias Mazen Elias

Sci Rep 2021 Apr 9;11(1):7814. Epub 2021 Apr 9.

Department of Internal Medicine C, Emek Medical Center, Afula, Israel.

Thrombin plays a central role in sepsis pathophysiology. The correlation of thrombin generation (TG) assays with infection severity and prognosis, and whether it can be used as a clinical tool, have been poorly explored and are the subjects of our research. We recruited 130 patients with systemic infection between 2016 and 2019. Read More

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April 2021
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Characteristics and potential sources of wintertime air pollution in Linfen, China.

Authors:
Lei Liu Xin Ma Wei Wen Chang Sun Jiao Jiao

Environ Monit Assess 2021 Apr 8;193(5):252. Epub 2021 Apr 8.

Beijing Polytechnic, Beijing, 100176, China.

Linfen in China's Shanxi Province suffers severe air pollution in winter. Understanding the characteristics of air pollution and providing scientific support to mitigate such pollution are urgent matters. This study investigated the variations of PM, PM, NO, SO, O, and CO in Linfen between December 1, 2019 and February 29, 2020. Read More

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April 2021
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