Pan Afr Med J 2020 14;35(Suppl 2). Epub 2020 Apr 14.
Department of Global Health and Development, London School of Hygiene and Tropical Medicine, United Kingdom.
Diagn Microbiol Infect Dis 2021 Oct 29;102(2):115587. Epub 2021 Oct 29.
SYNLAB Academy, Mannheim, Germany; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz; Medical Clinic V, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany. Electronic address:
Reliable diagnostic technologies are pivotal to the fight against COVID-19. While real-time reverse transcription-polymerase chain reaction (rRT-PCR) remains the gold standard, commercial assays for antibodies against (SARS-CoV-2) have emerged. We sought to examine 5 widely used commercial methods. Read More
Forensic Sci Int 2021 Nov 14;330:111106. Epub 2021 Nov 14.
DeKalb County Medical Examiner's Office, Decatur, GA, USA.
Objectives: We describe the experience of a busy metropolitan medical examiner's office in the United States and share our navigation of the COVID-19 autopsy decision-making process. We describe key gross and microscopic findings that, with appropriate laboratory testing, should direct a pathologist towards a COVID-19-related cause of death.Material And Methods: We performed a retrospective review of 258 suspected and/or confirmed COVID-19 associated deaths that occurred between March 5, 2020, and March 4, 2021. Read More
J Mycol Med 2021 Nov 18;32(1):101228. Epub 2021 Nov 18.
Centre of Excellence for Health, Immunity and Infections (CHIP), Rigshospitalet, Blegdamsvej 9, Copenhagen 2100, Denmark; Department of Infectious Diseases, Rigshospitalet, Copenhagen 2100, Denmark.
Mucormycosis has recently been recognized as a severe complication of COVID-19 with high fatality rates. We report a fatal case of COVID-19 associated mucormycosis (CAM) in a non-diabetic immunocompromised patient, who was first misdiagnosed and treated for COVID-19 associated aspergillosis (CAPA). The risk factors and initial clinical presentation of CAPA and CAM are similar, but CAM has a more aggressive course and CAPA and CAM are treated differently. Read More
J Mol Diagn 2021 Nov 23. Epub 2021 Nov 23.
Biology Faculty, Technion - Israel Institute of Technology, Haifa, Israel; Faculty of Computer Science, Technion - Israel Institute of Technology, Haifa, Israel.
Quantifying the detection rate of the widely used SARS-CoV-2 RT-qPCR test and its dependence on patient demographics and disease progression is key in designing epidemiological strategies. Analyzing 843,917 test results of 521,696 patients, for each patient, a 'positivity period' was defined between COVID-19 diagnosis and last positive test result. The fraction of positive tests within this period was then used to estimate detection rate. Read More
Clin Microbiol Infect 2021 Nov 23. Epub 2021 Nov 23.
National Centre for Infectious Diseases, Singapore; Tan Tock Seng Hospital, Singapore; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore. Electronic address:
Objectives: Highly effective vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been developed but variants of concerns are worrisome, especially B.1.617. Read More