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Dialysis Independence Following Combination Daratumumab, Thalidomide, Bortezomib, Cyclophosphamide, and Dexamethasone in Multiple Myeloma With Severe Renal Failure.

Authors:
Donald C Moore Justin R Arnall Amanda Janes Mauricio Pineda-Roman

Clin Lymphoma Myeloma Leuk 2020 07 7;20(7):e395-e398. Epub 2020 Apr 7.

Levine Cancer Institute, Concord, NC.

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http://dx.doi.org/10.1016/j.clml.2020.03.014DOI Listing
July 2020

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First-line daratumumab shows high efficacy and tolerability even in advanced AL amyloidosis: the real-world experience.

Authors:
G Jeryczynski M Antlanger F Duca C Binder-Rodriguez T Reiter I Simonitsch-Klupp D Bonderman R Kain M-T Krauth H Agis

ESMO Open 2021 Mar 2;6(2):100065. Epub 2021 Mar 2.

Division of Oncology, Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria; Division of Hematology and Hemostaseology, Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria. Electronic address:

Background: Daratumumab was the first monoclonal CD38 antibody with single-agent activity approved for the treatment of multiple myeloma. Moreover, daratumumab demonstrated high response rates in relapsed immunoglobulin light-chain (AL) amyloidosis.

Patients And Methods: In our single-center retrospective real-life case series, we analyzed the efficacy and safety of daratumumab as first-line treatment. Read More

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[The 486th case: chronic diarrhea and orthostatic hypotension].

Authors:
Q Wang Z B Long M Qian J Feng X X Guo A M Yang Y You G J Fei

Zhonghua Nei Ke Za Zhi 2021 Mar;60(3):284-288

Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.

A 57-year-old man was admitted to hospital with diarrhea for 10 months and dizziness for 4 months. The patient had 1-2 liters watery stool per day, without pyogenic blood or abnormality in gastroenteroscopy examination. The level of hemoglobin and albumin was generally normal, and fasting test was positive. Read More

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Tailored Treatment to MRD Response: A Phase I/II Study for Newly Diagnosed Multiple Myeloma Patients Using High Dose Twice-Weekly Carfilzomib (45 and 56 mg/m ) in Combination with Lenalidomide and Dexamethasone.

Authors:
Neha Korde Donna Mastey Elizabet Tavitian Sham Mailankody Alexander Lesokhin Hani Hassoun Eric L Smith Nikoletta Lendvai Malin Hultcrantz Urvi Shah Carlyn Tan Sydney Lu Benjamin Diamond Meghan Salcedo Kelly Werner David J Chung Michael Scordo Gunjan L Shah Oscar Lahoud Heather Landau Maria Arcila Caleb Ho Mikhail Roshal Ahmet Dogan Andriy Derkach Sean M Devlin Sergio A Giralt Ola Landgren

Am J Hematol 2021 Mar 4. Epub 2021 Mar 4.

Department of Medicine, Memorial Sloan Kettering Cancer Center, Multiple Myeloma Service, Miami, FL.

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March 2021
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Stem cell yield and transplantation in transplant-eligible newly diagnosed multiple myeloma patients receiving daratumumab + bortezomib/thalidomide/dexamethasone in the phase 3 CASSIOPEIA study.

Authors:
Cyrille Hulin Fritz Offner Philippe Moreau Murielle Roussel Karim Belhadj Lotfi Benboubker Denis Caillot Thierry Facon Laurent Garderet Frédérique Kuhnowski Anne-Marie Stoppa Brigitte Kolb Mourad Tiab Kon-Siong Jie Matthijs Westerman Jérôme Lambert Lixia Pei Veronique Vanquickelberghe Carla De Boer Jessica Vermeulen Tobias Kampfenkel Pieter Sonneveld Niels W C J Van de Donk

Haematologica 2021 Mar 4. Epub 2021 Mar 4.

Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Hematology, Amsterdam.

Not available. Read More

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Multiple myeloma with Echinococcus granulosus infection diagnosed by detection of oligoclonal bands: A case report.

Authors:
Jinghong Li Xiaoyun Zhang Hongjun Hao Shiheng Fan Yuming Xu

Medicine (Baltimore) 2021 Mar;100(9):e24709

Department of Neurology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province.

Rationale: Isoelectric focusing electrophoresis (IFE) is currently recognized as the gold standard for detecting oligoclonal bands (OCBs) in cerebrospinal fluid (CSF). To the best of our knowledge, however, no study has reported on type III OCBs using IFE. In this paper, we report on a rare case of multiple myeloma (MM) with Echinococcus granulosus infection diagnosed by IFE. Read More

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March 2021
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