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Pharmaceutics 2021 Feb 9;13(2). Epub 2021 Feb 9.

Department of Drug Technology and Social Pharmacy, Lithuanian University of Health Sciences, LT-50161 Kaunas, Lithuania.

Chewable gel tablets are an underdeveloped subject, even though there are many simple chewable tablets and gummy candies in the food and pharmaceutical industries. Chewable gel tablets are not as sweet, they can have an active substance, pharmacological effect, and a value of nutrition. The aim of this study was to prepare gelatin-based chewable tablets with as a preservative and to determine the shelf-life variability depending on storage conditions, and to evaluate texture changes. Read More

Eur Radiol 2021 Jan 26. Epub 2021 Jan 26.

Cardiovascular Imaging Research Center, Massachusetts General Hospital - Harvard Medical School, 165 Cambridge Street, Suite 400, Boston, MA, 02114, USA.

Objectives: The size of the heart may predict major cardiovascular events (MACE) in patients with stable chest pain. We aimed to evaluate the prognostic value of 3D whole heart volume (WHV) derived from non-contrast cardiac computed tomography (CT).

Methods: Among participants randomized to the CT arm of the Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE), we used deep learning to extract WHV, defined as the volume of the pericardial sac. Read More

J Indian Soc Pedod Prev Dent 2020 Oct-Dec;38(4):374-380

Department of Pedodontics and Preventive Dentistry, Mansarover Dental College, Bhopal, Madhya Pradesh, India.

Aim And Objectives: The aim and objectives of this study are to evaluate and compare the effectiveness of Myristica fragrans - Nutmeg, Terminalia chebula - Myrobolan, Ocimum sanctum-tulsi, and 2.5% sodium hypochlorite (NaOCl) on the removal of the smear layer by the scanning electron microscope (SEM).

Settings And Design: Endodontic treatment aims at disinfection and then obturation of root canal system in to prevent re-infection. Read More

J Gen Intern Med 2020 11 14;35(11):3271-3277. Epub 2020 Sep 14.

Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, USA.

Background: Black elderberry, used medicinally for centuries, decreased influenza duration by 4 days in three previous peer-reviewed trials. US elderberry sales, possibly related to a "high severity" and "high activity" influenza season from January to March 2018, more than doubled from 2017 to 2018 to > $100 million.

Objective: To determine whether elderberry extract decreases influenza's duration and severity. Read More

Eur Radiol 2021 Feb 27;31(2):1140-1150. Epub 2020 Aug 27.

Department of Radiology, Shengjing Hospital of China Medical University, No. 36 Sanhao Street, Heping District, Shenyang, 110004, Liaoning, China.

Objectives: This study was conducted to establish and validate a non-contrast T1 map-based radiomic nomogram for predicting major adverse cardiac events (MACEs) in patients with acute ST-segment elevation myocardial infarction (STEMI) undergoing percutaneous coronary intervention (PCI).

Methods: This retrospective study included 157 consecutive patients (training sets, 109 patients; test sets, 48 patients) with acute STEMI undergoing PCI. An open-source radiomics software was used to segment the myocardium on the non-contrast T1 mapping and extract features. Read More