Transcatheter Closure of Perimembranous Ventricular Septal Defects Using Different Generations of Amplatzer Devices: Multicenter Experience.

J Interv Cardiol 2020 21;2020:8948249. Epub 2020 Feb 21.

Pediatric Interventional Cardiology Department, National Institute of Cardiology "Ignacio Chávez", Mexico City, Mexico.

Objectives: To demonstrate safety and efficacy of using different generations of softer Amplatzer™ devices for ventricular septal defect (VSD) closure to avoid serious complications at follow-up.

Background: Transcatheter closure of perimembranous ventricular septal defects (PmVSD) is a well-established procedure; however, it is associated with unacceptable incidence of complete heart block. Great advantages have been achieved by using softer devices for VSD transcatheter closure. The first and second generation of Amplatzer™ occluders (AVP II, ADO, and ADO II) seem to offer a safe and attractive alternative for this procedure. These devices can be delivered using either an arterial (retrograde) or venous (prograde) approach.

Methods And Results: Patients with congenital PmVSD who underwent transcatheter closure using ADO, ADO II, and AVP II devices were included. Primary end point was to determine efficacy and safety of these generations of devices and to determine the incidence of complications at follow-up (complete AV block and aortic/tricuspid/mitral regurgitation). One hundred and nineteen patients underwent VSD closure at a median age of 5 years (8 months-54 years). During the catheterization, there were only minor complications and at follow-up of 36 ± 25.7 months (up to 99 months), the closure rate was high of 98.3% and freedom from AV block was 100%.

Conclusions: The use of softer Amplatzer™ devices is a good alternative to achieve PmVSD closure safely with no risk of AVB during the procedure or at midterm follow-up.

Download full-text PDF

Source
http://dx.doi.org/10.1155/2020/8948249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054803PMC
September 2020
1.318 Impact Factor

Publication Analysis

Top Keywords

transcatheter closure
16
ventricular septal
12
ado ado
8
septal defects
8
softer amplatzer™
8
amplatzer™ devices
8
vsd closure
8
closure perimembranous
8
complications follow-up
8
perimembranous ventricular
8
closure
7
devices
7
included primary
4
devices included
4
closure ado
4
ado avp
4
avp devices
4
primary point
4
efficacy safety
4
generations devices
4

Similar Publications