J Cataract Refract Surg 2020 02;46(2):319
Front Physiol 2021 17;12:683056. Epub 2021 Jun 17.
The Eye Center, Second Affiliated Hospital of School of Medicine, Zhejiang University, Hangzhou, China.
Cold cataract is the reversible opacification of the lens when the temperature decreases. However, we observed that when temperature of the rats' lens was maintained at a lower temperature for a prolonged time, the opacification of lens was only partly reversible. To review the potential molecular mechanism of the irreversible part of opacification under cold stimulation, we applied comparative transcriptomic and proteomic analysis to systematically investigate the molecular changes that occurred in the lens capsules of rats under low temperature treatments. Read More
J Ocul Pharmacol Ther 2021 04 26;37(3):172-180. Epub 2021 Jan 26.
Department of Biomaterials, School of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou, China.
The intraocular lens (IOL) is a common, yet important, implantable device used in treatment of cataract in clinics. However, the unexpected adhesion of postoperative residual lens epithelial cells (LECs) often causes serious complications, such as posterior capsular opacification (PCO), which lead to vision loss again. In this investigation, a poly(sulfobetaine methacrylate) (PSBMA) brush coating was fabricated on an IOL to generate a hydrophilic surface coating on the IOL for enhanced cell adhesion resistance so as to decrease PCO incidence. Read More
ACS Appl Mater Interfaces 2020 Sep 3;12(37):42193-42201. Epub 2020 Sep 3.
Polymeric and Soft Materials Laboratory, School of Chemical Engineering and Advanced Institute of Materials Science, Changchun University of Technology, Changchun 130012, China.
In recent years, the use of smart windows to adjust sunlight to achieve energy conversion has received increasing attention. In this paper, a novel smart window was easily prepared by using thermochromic hydrogels as an interlayer and indium tin oxide films as an electric heating layer. The shielding transmission rates of visible and near-infrared light reached 88. Read More
Transplant Proc 2020 Nov 23;52(9):2849-2853. Epub 2020 Jul 23.
Department of Pediatric Bone Marrow Transplantation, Oncology, and Hematology, Wroclaw Medical University, Wroclaw, Poland. Electronic address:
Peripheral blood hematopoietic stem cell mobilization is widely performed in a variety of clinical facilities and is believed to be a safe outpatient procedure. In this report, we describe a child with neuroblastoma who developed an extremely severe acute lung injury after granulocyte colony-stimulating factor was used for peripheral hematopoietic stem cell mobilization. A 3-year-old boy with a medical history of patent foramen ovale and secundum atrial septal defect was diagnosed with an MYCN-amplified neuroblastoma and treated with chemotherapy. Read More
J Immunother Cancer 2020 05;8(1)
Oncology, Georgetown Lombardi Comprehensive Cancer Center, Washington, DC, USA.
Background: Immune checkpoint inhibitors (ICIs) can produce specific immune-related adverse events including pneumonitis. The impact of ICI therapy on the severity of acute coronavirus infection symptomatology warrants further exploration.Case Presentation: We report a 65-year-old man diagnosed with stage IV melanoma who developed pulmonary and brain metastases and was treated with bilateral craniotomies followed by combined nivolumab and ipilimumab immunotherapy. Read More