Inflamm Bowel Dis 2020 04;26(5):e41
Department of Gastroenterology, Austin Health, Melbourne, Australia.
United European Gastroenterol J 2021 Mar;9(2):279
University of Birmingham Microbiome Treatment Centre, University of Birmingham, Birmingham, UK.
J Chin Med Assoc 2021 Apr 12. Epub 2021 Apr 12.
Division of Gastroenterology and Hepatology Endoscopic Center for Diagnosis and Therapy, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC Keelung Hospital, Ministry of Health Welfare, Keelung, Taiwan, ROC National Yang Ming Chiao Tung University, School of Medicine Institute of Biomedical Informatics, Taipei, Taiwan, ROC.
Background: Inflammatory bowel disease (IBD) is a chronic inflammatory disease associated with complicated interaction between immune, gut microbiota, and environmental factors in a genetically vulnerable host. Dysbiosis is often seen in patients with IBD. We aimed to investigate the fecal microbiota in patients with IBD and compared them to a control group in Taiwan. Read More
Therap Adv Gastroenterol 2021 31;14:17562848211004493. Epub 2021 Mar 31.
Section of Gastroenterology, Veterans Affairs Tennessee Valley Healthcare System, Nashville, TN.
The inflammatory bowel diseases (IBD), comprising Crohn's disease (CD) and ulcerative colitis (UC), are chronic, progressive, inflammatory conditions of the gastrointestinal tract. Imbalance in the gut microbial community, or dysbiosis, and the subsequent immune response, represent the critical relationship between genetic susceptibility, microbes, and environment factors, that result in IBD. Gastrointestinal pathogens - a common cause of dysbiosis - have been implicated as an environmental trigger in new onset IBD, as well as flare of existing IBD. Read More
Front Immunol 2021 1;12:648162. Epub 2021 Apr 1.
National-Local Joint Engineering Laboratory of Breeding and Cultivation of Edible and Medicinal Fungi, Soil and Fertilizer Institute, Sichuan Academy of Agricultural Sciences, Chengdu, China.
is an edible medicinal mushroom, and its polysaccharide components are found to confer various health benefits. This study identified the protective effects of polysaccharides of (TPs) against dextran sulfate sodium (DSS)-induced colitis in mice. High dose of TPs (HTPs) could prevent the colon from shortening, reduce activity of colonic myeloperoxidase and serum diamine oxidase (DAO), decrease the concentration of D-lactate, and alleviate the colonic tissue damage in colitic mice. Read More
EBioMedicine 2021 Apr 13;66:103329. Epub 2021 Apr 13.
Division of Gastroenterology, Department of Internal Medicine, University Hospital of North Norway, Tromsø, Norway.
Neutralizing tumour necrosis factor (TNF) antibodies have been widely used to treat inflammatory bowel disease (IBD) in the clinical practice. In this review, the principal biomarker analysis revealed that faecal calprotectin, C-reactive protein, serum or mucosal concentrations of anti-TNF monoclonal antibodies (mAbs) and antibodies to anti-TNF mAbs are commonly used as current biomarkers in the evaluation of anti-TNF therapeutic efficacy. However, mucosal cytokine transcripts. Read More