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Cereb Cortex 2021 Mar 2. Epub 2021 Mar 2.

Division of Neuropharmacology and Neurological Diseases, Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329, USA.

The synaptic organization of thalamic inputs to motor cortices remains poorly understood in primates. Thus, we compared the regional and synaptic connections of vGluT2-positive thalamocortical glutamatergic terminals in the supplementary motor area (SMA) and the primary motor cortex (M1) between control and MPTP-treated parkinsonian monkeys. In controls, vGluT2-containing fibers and terminal-like profiles invaded layer II-III and Vb of M1 and SMA. Read More

ESMO Open 2021 Mar 3;6(2):100073. Epub 2021 Mar 3.

Department of Translational Research and New Technologies in Medicine and Surgery, Unit of Medical Oncology, Azienda Ospedaliero-Universitaria Pisana, University of Pisa, Pisa, Italy. Electronic address:

Introduction: The consensus molecular subtypes (CMS) demonstrated prognostic value in metastatic colorectal cancer (mCRC). Similarly, a prognostic impact was suggested for the pre-consensus CRCAssigner (CRCA) classifier in early stages. The potential predictive role of these classifiers with regard to the choice of the first-line therapy has not been established. Read More

Eur J Cancer 2021 Feb 10;147:154-160. Epub 2021 Feb 10.

Department of Haematology and Medical Oncology, Clinic for Internal Medicine II, University Hospital Jena, Jena, Germany; Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Jena, Germany.

The worldwide spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the associated infectious coronavirus disease (COVID-19) has posed a unique challenge to medical staff, patients and their families. Patients with cancer, particularly those with haematologic malignancies, have been identified to be at high risk to develop severe COVID-19. Since publication of our previous guideline on evidence-based management of COVID-19 in patients with cancer, research efforts have continued and new relevant data has come to light, maybe most importantly in the field of vaccination studies. Read More

J Hazard Mater 2021 Feb 24;414:125488. Epub 2021 Feb 24.

Shanghai Key Lab for Urban Ecological Processes and Eco-Restoration, School of Ecological and Environmental Sciences, East China Normal University, Shanghai 200241, China.

Abiotic oxidation of toxic As(III) to As(V) is being deemed as a necessary step for the overall arsenic decontamination in both natural and engineered systems. Direct oxidation of As(III) by chemical oxidants, such as ozone, permanganate, ferrate, chlorine and chloramine, or naturally occurring minerals like Mn, Fe oxides, seems straightforward. Both O and HO are ineffective for arsenite oxidation, but they can be activated by reducing substances like Fe, Fe to increase the oxidation rates. Read More

Econ Hum Biol 2021 Feb 26;41:100993. Epub 2021 Feb 26.

Department of Social Sciences, Universidad Carlos III Madrid, Calle Madrid, 126 Getafe, CP: 28903, Madrid, Spain. Electronic address:

This paper examines the evolution of the statures of Spanish male and female migrants who entered Mexico between the mid-nineteenth and the mid-twentieth century. Using the information contained in the National Registry of Foreigners created by the Mexican government, the paper also estimates the evolution of the gap between male and female migrants' heights. The inclusion of women and their heights in the registry allows the estimation of both male and female heights and the analysis of their evolution for a group of comparable individuals. Read More