Gut Microbiota and Cardiometabolic Risk Factors in Hemodialysis Patients: A Pilot Study.

Top Clin Nutr 2019 Apr-Jun;34(2):153-160

Division of Nutritional Sciences, University of Illinois at Urbana-Champaign.

The gut microbiota has been implicated in the pathogenesis and progression of kidney disease. However, little is known about the gut microbiota in hemodialysis (HD) patients. We assessed the gut microbiota and its relationship with clinical variables in ten HD patients. We found that the -to- ratio was positively associated with traditional risk factors for cardiovascular disease. Furthermore, was positively associated with carbohydrate intake and negatively associated with arterial stiffness. Finally, endotoxemia was inversely associated with butyrate producers. Future studies should assess if targeting the gut microbiota result in a lower burden for cardiovascular disease in HD patients.

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Source
http://dx.doi.org/10.1097/TIN.0000000000000170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880937PMC
November 2019

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