A unique C-linked chalcone-dihydrochalcone dimer from resin.

Nat Prod Res 2019 Nov 7:1-6. Epub 2019 Nov 7.

Department of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.

A new C-linked chalcone-dihydrochalcone dimer, named dracidione, was isolated from the ethyl acetate extract of dragon's blood resin of Balf. f. Structure elucidation of the new compound was carried out by means of one- and two-dimensional NMR spectroscopy in addition to high resolution mass spectrometry. The unique structure incorporated a chalcone and a dihydrochalcone, which is reported for the first time from nature. Furthermore, dracidione showed moderate α-glucosidase inhibitory activity with IC= 40.27 µg/ml.

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http://dx.doi.org/10.1080/14786419.2019.1687471DOI Listing
November 2019

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