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Cell Commun Signal 2022 07 7;20(1):102. Epub 2022 Jul 7.

State Key Laboratory of Medicinal Chemical Biology, Frontiers Science Center for Cell Responses, College of Life Sciences, Nankai University, No. 94 Weijin Road, Tianjin, 300071, China.

Background: Circular dorsal ruffles (CDRs) are rounded membrane ruffles induced on the dorsal surfaces of cells stimulated by growth factors (GF). They can serve as signal platforms to activate AKT protein kinase. After GF stimulation, phosphatidylinositol 3-kinase (PI3K) generates phosphatidylinositol (3,4,5)-triphosphate (PIP3) in the plasma membrane. Read More

Phys Rev E 2022 May;105(5-2):055110

Department of Mechanical Engineering, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.

Acoustic radiation force and torque arising from wave scattering are able to translate and rotate matter without contact. However, the existing research mainly focused on manipulating simple symmetrical geometries, neglecting the significance of geometric features. For the nonspherical geometries, the shape of the object strongly affects its scattering properties, and thus the radiation force and torque as well as the acoustophoretic process. Read More

J Dig Dis 2022 Jun 9. Epub 2022 Jun 9.

Department of Gastroenterology, Chinese Academy of Medical Sciences, Peking Union Medical College Hospital, Beijing, China.

Objectives: Cronkhite-Canada syndrome (CCS) is a rare hamartomatous polyposis syndrome with a proposed association with chronic autoimmune inflammation. To date, genetic background of patients with CCS remains less investigated. In this study we aimed to explore the genomic landscape of CCS. Read More

Inorg Chem 2022 Jun 3;61(24):9283-9294. Epub 2022 Jun 3.

Jiangsu Key Laboratory for NSLSCS, School of Physical Science and Technology, Nanjing Normal University, Nanjing 210023, P.R. China.

Using Dy(dbm)(HO) and Dy(btfa)(HO) to react with enantiopure -donors, (-)/(+)-4,5-pinenepyridyl-2-pyrazine (L/L), respectively, two pairs of chiral Dy enantiomers, Dy(dbm)L/Dy(dbm)L (/) and Dy(btfa)L/Dy(btfa)L (/) were obtained, wherein one of the benzene rings of dbm (dibenzoylmethanate) in / is displaced by the -CF group of btfa (4,4,4-trifluoro-1-phenyl-1,3-butanedionate) in /. Interestingly, this substitution results not only in giant differences in their single-ion magnetic (SIM) performances but also in their completely different nonlinear optical (NLO) responses. presents a large effective energy barrier ( = 265. Read More

Cell Commun Signal 2022 05 31;20(1):77. Epub 2022 May 31.

Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration of Ministry of Education, Orthopedic Department of Tongji Hospital, Tongji University School of Medicine, Shanghai, 200065, People's Republic of China.

Background: Natural antisense RNAs are RNA molecules that are transcribed from the opposite strand of either protein-coding or non-protein coding genes and have the ability to regulate the expression of their sense gene or several related genes. However, the roles of natural antisense RNAs in the maintenance and myogenesis of muscle stem cells remain largely unexamined.

Methods: We analysed myoblast differentiation and regeneration by overexpression and knockdown of Foxk1-AS using lentivirus and adeno-associated virus infection in C2C12 cells and damaged muscle tissues. Read More