Large pulmonary sclerosing pneumocytoma with massive necrosis and vascular invasion: a case report.

Oxf Med Case Reports 2019 Jul;2019(7)

Department of Thoracic Surgery, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.

Pulmonary sclerosing pneumocytoma (PSP) is pathologically classified as an adenoma and behaves in a benign manner. However, some cases of PSP displayed pathologically malignant behavior, such as lymph node metastasis and necrosis. A 64-year-old woman was referred to our hospital complaining of a cough and breathlessness. Histopathological analysis of the resected specimen by left pneumonectomy and lymph node dissection revealed a large PSP measuring 15 × 14 cm in size, with massive necrosis and vascular invasion. This case was the largest ever reported and suggested that clinico-histological presentation of PSP sometimes showed an aggressive phenotype like advanced lung cancer.

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Source
http://dx.doi.org/10.1093/omcr/omz066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660061PMC
July 2019
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