Universal and label-free photosensitization colorimetric assays enabled by target-induced termini transformation of dsDNA resistant to Exo III digestion.

Chem Commun (Camb) 2019 Jun 5;55(50):7211-7214. Epub 2019 Jun 5.

Analytical & Testing Center, Sichuan University, 29 Wangjiang Road, Chengdu 610064, China. and College of Chemistry, Sichuan University, 29 Wangjiang Road, Chengdu 610064, China.

A label-free and universal photosensitization colorimetric assay based on target-induced dsDNA termini switching has been developed for the analysis of nucleic acids, proteins, small molecules and metal ions. This strategy is highly sensitive and versatile, the principle of which will be desirable for various biosensor developments and applications.

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http://dx.doi.org/10.1039/c9cc03551fDOI Listing
June 2019
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