Vitamin D Status in Egyptian Children With Allergic Rhinitis.

Ear Nose Throat J 2019 May 15:145561319850814. Epub 2019 May 15.

7 Faculty of Nursing, Department of Community Health Nursing, Assiut University, Assiut, Egypt.

Objective: This study aimed to assess the serum levels of vitamin D in an Egyptian cohort of children with allergic rhinitis (AR) and to evaluate any correlation of vitamin D status with the disease severity.

Patient And Methods: One hundred twenty children with AR and 100 healthy children were included in our study. We studied the serum levels of vitamin D 25(OH)D and 1,25(OH)2D in all participants. The associations between vitamin D levels and clinical characteristics of AR were examined.

Results: In AR group, the serum levels of calcium, (25(OH)D and 1,25(OH)2D levels were significantly lower ( p < .0001, p < .001, and p < .0001, respectively) in AR children than in controls. Furthermore, the mean 25-OHD3 levels in patients with moderate/severe AR were significantly lower than those with mild AR ( p < .001). We found significant negative correlations between mean 25(OH)D levels and total nasal symptom score ( r = -.62, p = .002) and total immunoglobulin E levels ( r = -.27, p = .013) in AR group.

Conclusions: Vitamin D deficiency is a frequent finding among Egyptian children with AR when compared to the healthy group. A significant inverse association was observed between vitamin D levels and AR disease severity.

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http://dx.doi.org/10.1177/0145561319850814DOI Listing
May 2019
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References

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Restimulia L et al.
Open Access Maced J Med Sci 2018

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