Clin Nutr 2019 08 1;38(4):1963-1964. Epub 2019 May 1.
Head of ICU & Research, Department of Intensive Care Medicine, Gelderse Vallei Hospital, Willy Brandtlaan 10, 6716 RP, Ede, the Netherlands. Electronic address:
Free Radic Biol Med 2021 Sep 22. Epub 2021 Sep 22.
Institute of Geriatrics, Affiliated People's Hospital of Nanchang University, Nanchang, Jiangxi, 330006, PR China; Department of Neurology, Affiliated People's Hospital of Nanchang University, Nanchang, Jiangxi, 330006, PR China. Electronic address:
Corneal alkali burn, as one of the most serious ophthalmic emergencies, is difficult to be cured by conservative treatments. It is well known that oxidative stress, inflammation, and neovascularization are the main causes of corneal damage after alkali burn, but its underlying mechanism remains to be elucidated. Here, we reported that the expression and phosphorylation (Ser616) of mitochondrial fission protein Drp1 were up-regulated at day 3 after alkali burn, while mitochondrial fusion protein Mfn2 was down-regulated. Read More
Toxicol Lett 2021 Sep 22. Epub 2021 Sep 22.
School of Forensic Medicine, Guizhou Medical University, Guiyang, China. Electronic address:
Methamphetamine (METH), a widely abused nervous system stimulant, could induce neurotoxicity through α-synuclein (α-syn). Not much is known about the neuronal derived α-syn transmission that underlies oligodendrocyte pathology in METH mice model. In this study, we tested α-syn level, oligodendroglial pathology and autophagy lysosome pathway (ALP) function in corpus callosum in a chronic METH mice model. Read More
Brain Res 2021 Sep 22:147665. Epub 2021 Sep 22.
Cognitive & Sports Neuroscience Laboratory, National Demonstration Center for Experimental Sports Science Education, College of Physical Education and Sports Science, South China Normal University, Guangzhou, Guangdong 510006, China. Electronic address:
DHED (10β,17β-dihydroxyestra-1,4-dien-3-one) is a brain-selective prodrug of 17β-estradiol and has been reported to have a strong neuroprotective effect. In this study, the exhaustive swimming rat model was used to investigate the therapeutic effects and mechanisms of intranasal DHED treatment. Male eight-week-old healthy Sprague Dawley rats were randomly divided into three groups: control group (Cont), exhaustive swimming (ES), and DHED + exhaustive swimming (DHED). Read More
Environ Sci Pollut Res Int 2021 Sep 25. Epub 2021 Sep 25.
Department of Zoology and Entomology, Helwan University, Cairo, 11795, Egypt.
Monosodium glutamate (MSG), a commonly used flavor enhancer, has been reported to induce hepatic and renal dysfunctions. In this study, the palliative role of protocatechuic acid (PCA) in MSG-administered rats was elucidated. Adult male rats were assigned to four groups, namely control, MSG (4 g/kg), PCA (100 mg/kg), and the last group was co-administered MSG and PCA at aforementioned doses for 7 days. Read More
Eur J Nutr 2021 Sep 24. Epub 2021 Sep 24.
Interdisciplinary Graduate Program in Advanced Convergence Technology and Science, Jeju National University, Jeju, 63241, Republic of Korea.
Purpose: Probiotics and prebiotics are commonly used to improve the gut microbiota. Since prebiotics can support the growth of probiotics, co-administration of these is called synbiotics. It has been demonstrated that obesity-induced gut dysbiosis can worsen inflammatory bowel disease symptoms. Read More