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Facial Plast Surg 2021 Feb 24. Epub 2021 Feb 24.

Department of Otorhinolaryngology - Head and Neck Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.

To date, an endonasal approach has not been described that combines different incisions to provide exposure of all of the key anatomical structures, allowing for adequate, comprehensive visualization of the nasal architecture including the complete quadrangular cartilage and its extension with the upper lateral cartilages, including the caudal septal border from the ventral border and anterior nasal spine to the anterior septal angle, the scroll, and internal nasal valve.The endonasal approach that Fausto Lopez-Infante designed, the FLI technique, combines several basic known endonasal incisions that together allow excellent access and great visualization of the intranasal surgical field, enables extensive septal work, and preserves the natural anatomy of the dorsum as well as the tip support structures.This technique and approach to nasal surgery are based on an understanding of anatomy, allow standardization of the surgery, and make it reproducible. Read More

J Pharm Pharm Sci 2021 ;24:94-112

Monash University Malaysia.

Since the discovery of its role in vitamin D metabolism, significant progress has been made in the understanding of gene organisation, protein structure, catalytic function, and genetic polymorphism of cytochrome P450 2R1 (CYP2R1). Located on chromosome 11p15.2, CYP2R1 possesses five exons, unlike most other CYP isoforms that carry nine exons. Read More

PLoS One 2021 24;16(2):e0247591. Epub 2021 Feb 24.

Amsterdam Institute for Global Health and Development (AIGHD), Amsterdam, The Netherlands.

Background: Globally, the possession of medicines stored at home is increasing. However, little is known about the determinants of possessing medicines, their usage according to clinical purpose, which we term 'correct drug match', and the role of health insurance.

Methods: This study uses data from a 2013 survey evaluating a health insurance program in Kwara State, Nigeria, which upgraded health facilities and subsidized insurance premiums. Read More

PLoS One 2021 24;16(2):e0246856. Epub 2021 Feb 24.

Department of Management, Lincoln International Business School, University of Lincoln, Lincoln, United Kingdom.

Little is known of how community assets can play a role in multimorbidity care provision. Using a rapid ethnographic approach, the study explored perceptions of the role of community assets in how multimorbidity is managed within Southwark and Lambeth in Southeast London, England. The scoping work comprised of four micro-studies covering (1) Rapid review of the literature (2) Documentary analysis of publicly available local policy documents (3) Thematic analysis of community stories and (4) Semi-structured stakeholder interviews. Read More

J Vis 2021 Feb;21(2):11

Department of Psychology, University of Cambridge, Cambridge, UK.

Visual motion perception underpins behaviors ranging from navigation to depth perception and grasping. Our limited access to biological systems constrains our understanding of how motion is processed within the brain. Here we explore properties of motion perception in biological systems by training a neural network to estimate the velocity of image sequences. Read More