PeerJ 2019 18;7:e6789. Epub 2019 Apr 18.
Department of Biomolecular Sciences, University of Urbino, Urbino, Pesaro-Urbino, Italia.
The aim of this work was to test and analyse the bioeffects of L. (Rosacaee) fruit ethanol extract on Schulze, 1883 (Placozoa) laboratory cultures which-for the first time-were employed as biological model to assess the bioactivity of a natural extract. The ethanol extract of was administrated during a 46 day experimental period; ultrastructural (by optical, confocal, TEM and SEM microscopy) and morphometric analyses indicated that treated showed significant differences in viability, reproductive modalities, body shape and colour with respect to the control group. Finally, bioactive compounds seem to exert profound protective effects on reproduction and phenotype. Our results may support additional investigations related to other bioactive compounds properties useful for nutraceutical preparations to be used as food supplements.