Complications Following Colonoscopy in a Nationwide Standard Cohort: A Retrospective Case-control Study.

Authors:
Ji Woo Kim
Ji Woo Kim
Busan St. Mary's Hospital
Su Young Kim
Su Young Kim
College of Medicine
South Korea
Jung Hye Choi
Jung Hye Choi
Hanyang University College of Medicine
Yun Tae Kim
Yun Tae Kim
Ajou University School of Medicine
Geunu Park
Geunu Park
Yonsei University
South Korea
Pr. Dae Ryong Kang, PhD
Pr. Dae Ryong Kang, PhD
Yonsei University, Wonju College of Medicine
Professor
Wonju, Gangwon-do | Korea, Republic of

Korean J Gastroenterol 2019 Mar;73(3):152-158

, Wonju; Department of Biostatistics, Yonsei University.

Background/aims: Despite the many reports of colonoscopy complications worldwide, few studies have been performed at the population level in Korea. In this study, a population-based study was performed to evaluate the incidence of post-colonoscopy perforations compared to a control group.

Methods: Between January 2011 and December 2011, data for all cases (age over 45) who underwent a colonoscopy were collected from National Health Insurance Service using a random sampling method. The clinical characteristics and perforation incidence (within 30 days after the colonoscopy) of cases were identified, and cases were then compared with controls who had not undergone a colonoscopy.

Results: Among 1,380,000 subjects, 31,177 cases and 62,354 controls were identified. Perforation occurred in 14 patients (0.04%) in the case group and one patient (<0.01%) in the control group (RR, 28.0; 95% CI 3.7-212.9, p<0.001). Subgroup analysis was followed according to the endoscopic procedure, gender and age. In subgroup analysis, colonoscopy-associated perforations occurred more in the therapeutic procedure (RR, 26; 95% CI 1.46-461.46), male (RR, 50; 95% CI 2.96-844.41), and age of 45-60 years (RR, 30; 95% CI 1.71-525.23).

Conclusions: A colonoscopy procedure is related to an increased risk of perforation at the population level. In addition, the therapeutic procedure, male, and age of 45-60 years appeared to be associated with an increased risk of perforation.

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Source
https://synapse.koreamed.org/DOIx.php?id=10.4166/kjg.2019.73
Publisher Site
http://dx.doi.org/10.4166/kjg.2019.73.3.152DOI Listing

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March 2019
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