[Trends on the epidemics of acute meningitis and encephalitis among population under 18 years-old in Shijiazhuang city, 2007-2017].

Authors:
J Li
J Li
University Hospital Hamburg-Eppendorf
X Zhang
X Zhang
College Station

Zhonghua Liu Xing Bing Xue Za Zhi 2019 Apr;40(4):417-421

Hebei Provincial Children Hospital, Shijiazhuang 050030, China.

To understand the trends on the epidemics of acute meningitis and encephalitis (AME) among children under 18 years-old in Shijiazhuang city, 2007-2017. Surveillance programs on acute meningitis and encephalitis (AMES) had been conducted in population less than 18 years-old, since 2007. Hospitals at county level or above in Shijiazhuang had been included to carry out the epidemiologic surveillance, including 6 on pathogens, regarding AMES. Qualitative description was performed to describe the epidemiologic patterns and pathogenic spectrums. Annual percent change (APC) was used to demonstrate the secular trends of AME. In 2007-2017, 11 222 locally developed AME cases that younger than 18 years-old, were reported in Shijiazhuang, with the annual average incidence rate as 108.62/100 000 (1 021/939 974) and APC as 4.81(95: 3.90-5.93)(=23.01, <0.001). Age-specific incidence appeared the highest among 4-5 years-old (242.96 cases per 100 000 children per year). Significant differences were found among children of other aged years except aged 0- years (aged 1- years =20.21, =0.004; aged 2- years =19.41, =0.006; aged 3- years =23.50, <0.001; aged 4- years =31.76, <0.001; aged 5- years =18.53, =0.008; aged 10-17 years =12.82, =0.023). The ratio of male to female was 1.46 ∶ 1 (6 652/4 570). The ratio of urban to rural cases was 0.28 ∶ 1 (2 456/8 766). A total of 57.73 (6 478/11 222) of the cases were seen between June and September. The overall positive rate of pathogens was 20.07 (658/3 123) among these patients. The top five pathogens appeared as Enterovirus (44.68, 264/658), Cryptococcus neoformans (9.12, 60/658), Japanese encephalitis virus (8.66, 57/658), Streptococcus pneumoniae (6.99, 47/658) and Varicella-zoster virus (6.69, 44/658). AME seriously harms the health of population under 18 years-old in Shijiazhuang city, with aged 3- years, aged 4- years in particular. Continued improvement on surveillance and expanded immunization are important to AME prevention and control.

Download full-text PDF

Source
http://dx.doi.org/10.3760/cma.j.issn.0254-6450.2019.04.009DOI Listing
April 2019
3 Reads

Publication Analysis

Top Keywords

acute meningitis
12
meningitis encephalitis
12
shijiazhuang city
8
population years-old
8
years-old shijiazhuang
8
epidemics acute
8
annual percent
4
spectrums annual
4
pathogenic spectrums
4
percent change
4
patterns pathogenic
4
change apc
4
secular trends
4
demonstrate secular
4
apc demonstrate
4
epidemiologic patterns
4
included carry
4
qualitative description
4
pathogens ames
4
including pathogens
4

Similar Publications