Evaluation of Placental Perfusion Based on Intravoxel Incoherent Motion Diffusion Weighted Imaging (IVIM-DWI) and Its Predictive Value for Late-Onset Fetal Growth Restriction.

Geburtshilfe Frauenheilkd 2019 Apr 12;79(4):396-401. Epub 2018 Dec 12.

Department of Medical Image, Guangzhou Women and Children's Medical Center, Guangzhou, China.

The aim of this study was to investigate placental blood perfusion in middle and late pregnancy and explore its predictive value for fetal growth restriction (FGR). All pregnant women included in the study were examined using placental intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI). Three IVIM parameters (D, f, D*) were obtained for each pregnant woman and analyzed using Image J software. Perfusion fraction f is a radiological marker of placental perfusion. The pulsatility index (PI) of the uterine artery is used to indirectly evaluate placental function. f-values were significantly lower in the late-onset FGR group compared to the normal late pregnancy group (19.07 vs. 27.78%). In addition, uterine artery PI values were markedly increased in the late-onset FGR group compared to the normal late pregnancy group (1.96 vs. 1.03), and neonatal weight was significantly lower in the late-onset FGR group (2.75 vs. 3.18 kg). There was a significant positive correlation between f-value, uterine artery PI and neonatal weight (r = 0.968, p < 0.01; r = 0.959, p < 0.01). There was a significant negative correlation between f-value and age of gestation (r = - 0.534, p < 0.01). Perfusion fraction f was strongly correlated with uterine artery blood flow resistance as measured by color Doppler and had a certain predictive value for late-onset FGR.

Download full-text PDF

Source
http://www.thieme-connect.de/DOI/DOI?10.1055/a-0717-5275
Publisher Site
http://dx.doi.org/10.1055/a-0717-5275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461467PMC

Still can't find the full text of the article?

We can help you send a request to the authors directly.
April 2019
14 Reads

Publication Analysis

Top Keywords

late-onset fgr
12
uterine artery
12
fgr group
12
late pregnancy
12
pregnancy group
8
fetal growth
8
imaging ivim-dwi
8
growth restriction
8
compared normal
8
neonatal weight
8
group compared
8
lower late-onset
8
normal late
8
intravoxel incoherent
8
placental perfusion
8
incoherent motion
8
group
5
marker placental
4
radiological marker
4
r = 0968 p 
4

Similar Publications