The ellagitannin trimer rugosin G inhibits recombinant human histidine decarboxylase.

Authors:
Yoko Nitta
Yoko Nitta
University of Hyogo
Japan
Hideyuki Ito
Hideyuki Ito
Okayama University
Japan
Hirohumi Komori
Hirohumi Komori
University of Hyogo
Japan
Hiroshi Ueno
Hiroshi Ueno
Osaka University
Japan
Mikiko Ito
Mikiko Ito
Institute of Health Biosciences
Oxford | United Kingdom
Motoyoshi Sakaue
Motoyoshi Sakaue
Kobe University Graduate School of Medicine
Japan
Hiroe Kikuzaki
Hiroe Kikuzaki
Osaka City University
Japan

Biosci Biotechnol Biochem 2019 Apr 17:1-4. Epub 2019 Apr 17.

e Department of Food Science and Nutrition , Nara Women's University , Kitauoyanishi-machi, Nara , Japan.

Rugosin G, an ellagitannin trimer, was isolated from the water-soluble fraction of red rose petals, and its inhibitory activity against recombinant human histidine decarboxylase was investigated. Rugosin G showed potent inhibition compared to ellagitannin monomers and a dimer with macrocyclic structure (oenothein B), suggesting the potent inhibition of rugosin G was attributed to its linear oligomeric conformation. Abbreviations: HDC, histidine decarboxylase; MeCO, acetone; EtOAc, ethyl acetate.

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https://www.tandfonline.com/doi/full/10.1080/09168451.2019.1
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http://dx.doi.org/10.1080/09168451.2019.1606695DOI Listing
April 2019
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References

(Supplied by CrossRef)
Article in J Home Econ Jpn
Nitta Y et al.
J Home Econ Jpn 2008

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