Most common histopathological patterns of the Minas Gerais Association of the Centers of Nephrology.

Authors:
Yoshimi Watanabe
Yoshimi Watanabe
Nagoya Institute of Technology
Japan
Alba Otoni
Alba Otoni
Federal University of Minas Gerais
Brazil
Sergio Wyton Pinto
Sergio Wyton Pinto
Hospital São João de Deus

Rev Assoc Med Bras (1992) 2019 Mar 11;65(3):441-445. Epub 2019 Apr 11.

MD, Nephrologist, MSc in Science from Unifesp, São Paulo/ São João de Deus Hospital - Brasil.

Introduction: We analyzed the distribution and frequency of glomerular diseases in patients biopsied between 1992 and 2016 in centers that make up the AMICEN (Minas Gerais Association of Nephrology Centers).

Methods: We analyzed the biopsy reports of patients from 9 AMICEN nephrology centers. We took note of their age, gender, ultrasound use, post-biopsy resting time, whether the kidney was native or a graft, number of glomeruli and indication for the biopsy. The kidney biopsy findings were broken down into four categories: glomerular and non-glomerular diseases, normal kidneys and insufficient material for analysis. Those patients diagnosed with glomerular diseases were further divided into having primary or secondary glomerular diseases.

Results: We obtained 582 biopsy reports. The median age was 38 years (1 to 85). The number of glomeruli varied between 0 and 70 (median = 13.0). In total, 97.8% of the biopsies were ultrasound guided. The main indication was nephrotic syndrome (36.9%), followed by hematuria-proteinuria association (16.2%). Primary glomerular diseases proved to be the most frequent (75.3%), followed by secondary diseases (24.7%). Among the primary glomerular diseases, FSGS was found at a higher frequency (28.8%), while among the secondary diseases, SLE was the most prevalent (42.4%). Regarding prevalence findings, those for both primary and secondary diseases were similar to those found in the large Brazilian registries published thus far.

Conclusion: Glomerular disease registries are an important tool to identify the prevalence of such disease in regions of interest and can serve as an instrument to guide public policy decisions concerning the prevention of terminal kidney diseases.

Download full-text PDF

Source
http://dx.doi.org/10.1590/1806-9282.65.3.441DOI Listing
March 2019
1 Read

Publication Analysis

Top Keywords

glomerular diseases
16
secondary diseases
12
diseases
9
number glomeruli
8
gerais association
8
primary secondary
8
minas gerais
8
primary glomerular
8
biopsy reports
8
glomerular
7
median 130
4
ultrasound guided
4
biopsies ultrasound
4
total 978%
4
130 total
4
978% biopsies
4
indication nephrotic
4
hematuria-proteinuria association
4
association 162%
4
162% primary
4

References

(Supplied by CrossRef)
Padrões histopatológicos das doenças glomerulares no Amazonas
Cardoso ACD et al.
J Bras Nefrol. 2006
Aspiration biopsy of the kidney 1951
Iversen P et al.
Am J Med. 1951
Biópsia renal: experiência do Hospital Geral de Goiânia
Oliveira VS et al.
J Bras Nefrol. 2004
Knowledge of renal histology alters patients management in over 40% of cases
Richards NT et al.
Nephrol Dial Transplant. 1994

Barros RT et al.
2006
Epidemiología de las glomerulopatías primarias en el Uruguay
Mazzuchi Frantchez N et al.
Arch Med Interna. 1997

Andrade LCF et al.
2004

Similar Publications