Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Background And Aims: Although the incidence of inflammatory bowel disease (IBD) is increasing in Asia, data on long-term epidemiologic trends are limited. We performed a 30-year longitudinal study to investigate temporal trends in the epidemiology of Crohn's disease (CD) and ulcerative colitis (UC) in Seoul, Korea.
Methods: This population-based study included 1431 IBD patients (418 CD, 1013 UC) diagnosed between 1986 and 2015 in the Songpa-Kangdong district of Seoul, Korea. Temporal trends in incidence, prevalence, and disease phenotype at diagnosis were analyzed.
Results: The adjusted mean annual incidence rates of CD and UC per 100,000 inhabitants increased from 0.06 (95% confidence interval [CI], 0.05-0.07) and 0.29 (95% CI, 0.27-0.31), respectively, in 1986-1990 to 2.44 (95% CI, 2.38-2.50) and 5.82 (95% CI, 5.73-5.92), respectively, in 2011-2015. Average annual percentage change in IBD incidence was 12.3% in 1986-1995, 12.3% in 1996-2005, and 3.3% in 2006-2015. The male-to-female ratio of the adjusted incidence rate was 3.3:1 for CD and 1.2:1 for UC. Perianal fistula/abscess was present in 43.3% of patients before or at CD diagnosis. At diagnosis, 54.3% of UC patients presented only with proctitis. The adjusted prevalence rate in 2015 was 31.59/100,000 (95% CI, 31.10-32.07) for CD and 76.66/100,000 (95% CI, 75.91-77.42) for UC.
Conclusions: The incidence and prevalence of IBD in Korea have continued to increase over the past three decades. Korean patients have distinct demographic and phenotypic characteristics including a male predominance and high frequency of perianal fistula/abscess in CD and high proportion of proctitis in UC.
We have submitted your request - we will update you on status within the next 48 hours.
Sign up for further access to Scientific Publications and Authors!
What are PubFacts Points?
PubFacts points are rewards to PubFacts members, which allow you to better promote your profile and articles throughout PubFacts.com
How do I earn PubFacts Points?
Each member is given 50 PubFacts points upon signing up. You can earn additional points by completing 100% of your profile, creating and participating in discussions, and sharing other members research.
What can I do with PubFacts Points?
Currently, you can use PubFacts Points to promote and increase readership of your articles.