A Rhinofacial Fungal Infection Presenting as an Intranasal Tumour.

Authors:
Annelyse Ballin
Annelyse Ballin
Federal University of Parana
David Saxton
David Saxton
Al Zahra Hospital
Egypt
Arunaloke Chakrabarti
Arunaloke Chakrabarti
Postgraduate Institute of Medical Education and Research
India

Sultan Qaboos Univ Med J 2018 Nov 28;18(4):e549-e552. Epub 2019 Mar 28.

Center of Advanced Research in Medical Mycology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.

Conidiobolomycosis is a rare fungal infection that affects adults in tropical regions. We report a 42-year-old male patient who was referred to the Sulaiman Al Habib Hospital, Dubai, United Arab Emirates (UAE), in 2013 with excessive nasal bleeding and a suspected nasal tumour. He reported having briefly visited central India nine months previously. Computed tomography and magnetic resonance imaging showed a highly vascularised mass in the nasal cavity. However, after surgical excision, initial treatment with amphotericin B deoxycholate was unsuccessful and the disease progressed, leading to external and internal nasal deformation and necessitating further excision and facial reconstruction. Histopathological analysis of the second biopsy revealed Splendore-Hoeppli changes consistent with a fungal infection. Microbiological findings subsequently confirmed . Subsequently, the patient was successfully treated with a combination of itraconazole and fluconazole. To the best of the authors' knowledge, this is the first report of a case of rhinofacial conidiobolomycosis from the UAE.

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Source
https://journals.squ.edu.om/index.php/squmj/article/view/300
Publisher Site
http://dx.doi.org/10.18295/squmj.2018.18.04.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443265PMC
November 2018
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