Quasi-experimental causality in neuroscience and behavioural research.

Authors:
Patrick N Lawlor
Patrick N Lawlor
Northwestern University
Urdaneta City | Philippines
Konrad P Kording
Konrad P Kording
Northwestern University and Rehabilitation Institute of Chicago
United States

Nat Hum Behav 2018 Dec 26;2(12):891-898. Epub 2018 Nov 26.

Departments of Neuroscience and Bioengineering, Leonard Davis Institute, Warren Center for Network Science, Wharton Neuroscience Initiative, University of Pennsylvania, Philadelphia, PA, USA.

In many scientific domains, causality is the key question. For example, in neuroscience, we might ask whether a medication affects perception, cognition or action. Randomized controlled trials are the gold standard to establish causality, but they are not always practical. The field of empirical economics has developed rigorous methods to establish causality even when randomized controlled trials are not available. Here we review these quasi-experimental methods and highlight how neuroscience and behavioural researchers can use them to do research that can credibly demonstrate causal effects.

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41562-018-0466-5DOI Listing
December 2018

Publication Analysis

Top Keywords

neuroscience behavioural
8
controlled trials
8
establish causality
8
randomized controlled
8
empirical economics
4
economics developed
4
field empirical
4
developed rigorous
4
causality practical
4
standard establish
4
rigorous methods
4
trials gold
4
practical field
4
causality randomized
4
researchers credibly
4
behavioural researchers
4
credibly demonstrate
4
demonstrate causal
4
causal effects
4
highlight neuroscience
4

References

(Supplied by CrossRef)
Article in Ann. Intern. Med.
F Grodstein et al.
Ann. Intern. Med. 2000
Article in N. Engl. J. Med.
JE Manson et al.
N. Engl. J. Med. 2003
Article in Ann. Intern. Med.
LL Humphrey et al.
Ann. Intern. Med. 2002
Article in Epidemiology
S Greenland et al.
Epidemiology 1990
Article in Lancet
F Ismail-Beigi et al.
Lancet 2010
Article in J. Am. Med. Assoc.
TA Officers et al.
J. Am. Med. Assoc. 2002
Article in N. Engl. J. Med.
SR Group et al.
N. Engl. J. Med. 2015
Article in Econometrica
CW Granger et al.
Econometrica 1969
Article in Am. Econ. Rev.
EE Leamer et al.
Am. Econ. Rev. 1983
Article in J. Educ. Psychol.
DL Thistlethwaite et al.
J. Educ. Psychol. 1960

Similar Publications