Hemolymphangioma involving bones and bladder detected on 68Ga-NEB PET/CT: A rare case report.

Authors:
Guozhu Hou
Guozhu Hou
General Hospital of Pingmei Shenma Medical Group Pingdingshan 467000
Pingdingshan | China
Yuanyuan Jiang
Yuanyuan Jiang
Wayne State University School of Medicine
United States
Shan Jian
Shan Jian
Sichuan University
China
Wuying Cheng
Wuying Cheng
Peking Union Medical College Hospital

Medicine (Baltimore) 2019 Apr;98(15):e15213

Department of Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College.

Rationale: Hemolymphangioma is a rare developmental defect of combined vasal and lymphatic vasculature. It is very rare that hemolymphangioma affects the bones and bladder simultaneously, and this condition has never been reported in PubMed.

Patient Concerns: A 12-year-old male has a history of hospitalization for recurrent episodes of chyluria of 8 years duration and progressively worsening gross hematuria with right hip pain for 6 months.

Diagnosis: Chylous test of urine fluid was positive. There was no organic disease in the kidneys. Ga-NOTA-Evans Blue (NEB) positron emission tomography/computed tomography (PET/CT) images demonstrated clearly several round and strip-shaped low-density shadows with mildly increased radioactive uptake in both bladder wall and pelvis, including sacral, pubic, and ischial bones. Histopathological analysis of biopsy on pubic and ischial bones confirmed the diagnosis of hemolymphangioma.

Interventions: The patient received treatment with traditional Chinese medicine.

Outcomes: At the 6-month follow-up visit, the patient's symptoms of chyluria, hematuria, and pain were all mitigated.

Lessons: Hemolymphangioma is a rare benign disease. Ga-NEB PET/CT is a specific method for the lymphatic system, and it might provide more accurate and comprehensive information about the disorder of the lymphatic system compared with CT and magnetic resonance imaging. When patients suffer from suspected lesions of the lymphatic system, Ga-NEB PET/CT might be recommended.

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Source
http://Insights.ovid.com/crossref?an=00005792-201904120-0008
Publisher Site
http://dx.doi.org/10.1097/MD.0000000000015213DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485884PMC

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April 2019
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