Unusual Presentation of Hemophagocytic Lymphohistiocytosis in a Kidney Transplant Patient.

Authors:
Danwen Yang
Danwen Yang
College of Pharmacy Health Sciences
Detroit | United States
Natanong Thamcharoen
Natanong Thamcharoen
Bassett Medical Center and Columbia University College of Physicians and Surgeons
United States
Andreas Varkaris
Andreas Varkaris
Department of Clinical Therapeutics
Greece
William Aird
William Aird
Beth Israel Deaconess Medical Center
Eliyahu V Khankin
Eliyahu V Khankin
Harvard Medical School
United States
Francesca Cardarelli
Francesca Cardarelli
Emory University

Case Rep Transplant 2019 10;2019:3682378. Epub 2019 Mar 10.

Division of Nephrology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

We are presenting a case of a middle-aged woman with history of remote kidney transplantation who had multiple admissions for septic shock-like picture, recurrent fever, and hypotension. Her shock manifestation would resolve after stress dose steroid administration and less than 24 hours of vasopressor administration. Initially, extensive workup was performed without revealing etiology. Eventually, a bone marrow biopsy was carried out leading to the diagnosis of hemophagocytic lymphohistiocytosis, most likely related to recent cytomegalovirus infection.

Download full-text PDF

Source
http://dx.doi.org/10.1155/2019/3682378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431471PMC
March 2019
1 Read

Publication Analysis

Top Keywords

hemophagocytic lymphohistiocytosis
8
dose steroid
4
stress dose
4
steroid administration
4
administration hours
4
vasopressor administration
4
hours vasopressor
4
resolve stress
4
hypotension shock
4
shock-like picture
4
septic shock-like
4
picture recurrent
4
recurrent fever
4
administration initially
4
fever hypotension
4
manifestation resolve
4
extensive workup
4
carried leading
4
biopsy carried
4
leading diagnosis
4

References

(Supplied by CrossRef)

Similar Publications