Uropathogens and their antimicrobial resistance patterns: Relationship with urinary tract infections.

Authors:
Ali Shariq
Ali Shariq
Dr. Ziauddin University Hospital
Abdulaziz Ajlan Alsalloom
Abdulaziz Ajlan Alsalloom
College of Medicine
Ibrahim H Babikir
Ibrahim H Babikir
College of Medical Laboratory Sciences

Int J Health Sci (Qassim) 2019 Mar-Apr;13(2):48-55

Department of Pathology and Laboratory Medicine, College of Medicine, Qassim University, Saudi Arabia.

Objectives: This study was performed to determine the prevalence of uropathogens causing urinary tract infections (UTIs) and to determine their pattern of antimicrobial resistance.

Methods: This study was conducted on 273 urine samples collected from outpatient departments (OPDs) of Qassim University affiliated hospitals. Fully automated VITEK 2 compact system was used in the identification and antimicrobial susceptibility testing of causative microorganisms.

Results: Of 273 urine samples, only 89 (32.6%) were found to show significant growth for UTI, and overall, drug resistance was found in 92% ( = 82/89) of samples, with most (80%) being resistant to at least two drugs. Antibiotic resistance was commonly observed in ampicillin (88.3%), piperacillin (72.7%), clindamycin (66.7%), amoxicillin/clavulanic acid (66.2%), and trimethoprim/sulfamethoxazole (50%). The commonly isolated microorganisms were 24 (27%), 11 (12.4%), 4 (4.5%), 4 (4.5%), 5 (5.6%) 5 (5.6%), and 3 (3.4%).

Conclusions: This research work has shown that patients with UTI in Qassim are at high risk of antibiotic resistance. The work also showed that multidrug-resistant bacteria can lead to momentous therapeutic problems in OPD patients.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436442PMC
April 2019

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