Effective noninvasive body contouring by using a combination of cryolipolysis, injection lipolysis, and shock waves.

Authors:
Matthias Sandhofer
Matthias Sandhofer
Austrian Academy of Cosmetic Surgery and Aesthetic Medicine. dr.matthias@sandhofer.at
Christel Weiss
Christel Weiss
University of Heidelberg
Germany
Gerhard Sattler
Gerhard Sattler
University of British Columbia
Canada
Neil S Sadick
Neil S Sadick
Weill Medical College of Cornell University
United States

J Cosmet Dermatol 2019 Apr 13. Epub 2019 Apr 13.

Department of Dermatology, Weill Cornell Medical College, New York, New York.

Background: Cryolipolysis combined with shockwave therapy has been previously shown to have synergistic effects in body contouring results.

Objective: This open-label, prospective, multicenter, comparative study investigated the safety and efficacy of combined cryolipolysis, shockwave therapy with cryolipolysis, shockwave therapy, and injection polyenylphosphatidylcholine-based lipolysis.

Methods: Enrolled patients were treated in the abdominal or flank area with cryolipolysis, shockwave therapy and injection lipolysis (n = 10) or cryolipolysis and shockwave therapy (n = 4). All treatments were conducted the same day. Evaluations were conducted 3 months after treatment and included histological analysis, standardized photography, blinded-investigator efficacy, and safety ratings, as well as patient ratings of satisfaction and tolerance.

Results: Compared to baseline, the 3-month follow-up histological analysis revealed a more profound subcutaneous adipose tissue reaction with the triple combination therapy (cryolipolysis, injection lipolysis, radial shock wave) than with the double combination with regard to adipocyte damage and grade of inflammation. Waist circumference was significantly reduced in patients of both groups, but patients in the triple combination group were shown to have a significantly more pronounced reduction in subcutaneous fat. Factors that were shown to influence treatment outcome included baseline BMI and waist circumference. Age and gender had no effect. The abdominal area reacted better to the treatment compared to flanks. No significant side effects or adverse events were reported. The procedure was well-tolerated, and the majority of patients were satisfied with the treatment results.

Conclusions: Combination of cryolipolysis, radial shockwave, and injection lipolysis is a safe, well-tolerated treatment for reduction in subcutaneous fat.

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Source
http://dx.doi.org/10.1111/jocd.12953DOI Listing
April 2019

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