Comparative study of subchronic toxicities of mosquito repellents (coils, mats and liquids) on vital organs in Swiss albino mice.

Authors:
Dr. Mehnaz Kamal, PhD
Dr. Mehnaz Kamal, PhD
College of Pharmacy, Prince Sattam Bin Abdulaziz University
Assistant Professor
Medicinal chemistry
Al Kharj, Riyadh | Saudi Arabia

Saudi Pharm J 2019 Mar 6;27(3):348-353. Epub 2018 Dec 6.

Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.

The aim of the current study was to evaluate and compare the toxicities of different types of mosquito repellents i.e. coils, mats and liquid vapors in animal models. Different types of mosquito repellents including liquid vaporizers, coils and mats have been extensively used by the people to get protection from the mosquitoes and diseases associated with them. The active constituents of these repellents include; allethrins, pyrethrins, paraffin and various other derivatives, are well known for their toxicities. Exposure of albino mice to these repellents for 3 h per day over a period of 20 days produced significant toxicological effects on vital body organs including; liver, lungs, kidneys, brain and heart. The order of toxicity of different repellents on nervous and hepatic tissues was found to be: Coil > Liquid > Mat while in renal and cardiac tissues, the coil was again found to be the most toxic one, mat with medium toxicity whereas liquid as least toxic (Coil > Mat > liquid). Lungs tissues are almost equally affected by all the repellants. On the basis of current findings, it has been concluded that exposure to various types of mosquito repellents can be deleterious to health and can cause various health related issues by producing pathological changes in the vital organs.

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Source
https://linkinghub.elsevier.com/retrieve/pii/S13190164183047
Publisher Site
http://dx.doi.org/10.1016/j.jsps.2018.12.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438702PMC
March 2019
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