Safety of Oral and Intravenous Iron.

Authors:
Thomas G Deloughery
Thomas G Deloughery
Oregon Health and Science University
United States

Acta Haematol 2019 10;142(1):8-12. Epub 2019 Apr 10.

Division of Hematology/Medical Oncology, Department of Pathology and Pediatrics, Oregon Health and Science University, Portland, Oregon, USA,

As the adverse effects of iron deficiency are better recognized, the use of oral and intravenous iron has increased dramatically. Oral iron is often poorly tolerated, with up to 70% or more of patients noting gastrointestinal issues; this may affect adherence to therapy. In addition, many patients will not respond to oral iron due to their underlying illness. Intravenous iron is being used more frequently to replete iron stores. True anaphylaxis is very rare, but complement-mediated infusion reactions may be seen in up to 1 in every 200 patients. Previous concerns about intravenous iron increasing the risk of infection or cardiovascular disease are unfounded.

Download full-text PDF

Source
http://dx.doi.org/10.1159/000496966DOI Listing

Still can't find the full text of the article?

We can help you send a request to the authors directly.
April 2019
14 Reads

Publication Analysis

Top Keywords

intravenous iron
16
iron
8
oral iron
8
oral intravenous
8
iron frequently
4
illness intravenous
4
underlying illness
4
iron underlying
4
replete iron
4
iron stores
4
frequently replete
4
will respond
4
affect adherence
4
issues affect
4
adherence therapy
4
therapy addition
4
stores true
4
addition patients
4
respond oral
4
rare complement-mediated
4

Altmetric Statistics

Similar Publications