A viral metagenomic survey identifies known and novel mammalian viruses in bats from Saudi Arabia.

Authors:
Nischay Mishra
Nischay Mishra
National Institute of Virology
India
Shamsudeen F Fagbo
Shamsudeen F Fagbo
Public Health Directorate
Abdulaziz N Alagaili
Abdulaziz N Alagaili
College of Science
State College | United States
Adam Nitido
Adam Nitido
University of California
Mr. Simon H Williams, BSc (Hons)
Mr. Simon H Williams, BSc (Hons)
Center for Infection and Immunity
Staff Associate
New York, NY | United States
James Ng
James Ng
University of California
Bohyun Lee
Bohyun Lee
Columbia University

PLoS One 2019 10;14(4):e0214227. Epub 2019 Apr 10.

Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, New York, United States of America.

Bats are implicated as natural reservoirs for a wide range of zoonotic viruses including SARS and MERS coronaviruses, Ebola, Marburg, Nipah, Hendra, Rabies and other lyssaviruses. Accordingly, many One Health surveillance and viral discovery programs have focused on bats. In this report we present viral metagenomic data from bats collected in the Kingdom of Saudi Arabia [KSA]. Unbiased high throughput sequencing of fecal samples from 72 bat individuals comprising four species; lesser mouse-tailed bat (Rhinopoma hardwickii), Egyptian tomb bat (Taphozous perforatus), straw-colored fruit bat (Eidolon helvum), and Egyptian fruit bat (Rousettus aegyptiacus) revealed molecular evidence of a diverse set of viral families: Picornaviridae (hepatovirus, teschovirus, parechovirus), Reoviridae (rotavirus), Polyomaviridae (polyomavirus), Papillomaviridae (papillomavirus), Astroviridae (astrovirus), Caliciviridae (sapovirus), Coronaviridae (coronavirus), Adenoviridae (adenovirus), Paramyxoviridae (paramyxovirus), and unassigned mononegavirales (chuvirus). Additionally, we discovered a bastro-like virus (Middle East Hepe-Astrovirus), with a genomic organization similar to Hepeviridae. However, since it shared homology with Hepeviridae and Astroviridae at ORF1 and in ORF2, respectively, the newly discovered Hepe-Astrovirus may represent a phylogenetic bridge between Hepeviridae and Astroviridae.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0214227PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457491PMC
April 2019
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References

(Supplied by CrossRef)
Education to Action: Improving Public Perception of Bats
E Hoffmaster et al.
Animals (Basel) 2016
Assessment of potential zoonotic disease exposure and illness related to an annual bat festival—Idanre, Nigeria
NM Vora et al.
MMWR Morb Mortal Wkly Rep 2014

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