Objectives: To assess the value of bee products with respect to antiviral efficacy against herpes viruses.
Design: A systematic review was done using the JUSTfind System of the Justus-Liebig-University Gießen and Scopus.
Results: Three trials on honey and 6 trials on propolis were conducted. Each trial provided evidence that these two bee products are interesting alternatives to acyclovir, especially propolis, which was found to be superior to acyclovir in 4 trials.
Conclusions: The evidence from these trials suggests that propolis is the best of all natural possibilities in the treatment of herpetic skin lesions, especially those related to HSV-1. Future studies should analyse if propolis could be an adjunct to treatment with acyclovir. For lesions in the oral cavity, honey could be an interesting alternative.
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