Seroprevalence of in domestic pigs, sheep, cattle, wild boars, and moose in the Nordic-Baltic region: A systematic review and meta-analysis.

Authors:
Abbey Olsen
Abbey Olsen
Wageningen University
Wageningen | Netherlands
Rebecca Berg
Rebecca Berg
Veterinary Medical Teaching Hospital
United States
Maarja Tagel
Maarja Tagel
Institute of Veterinary Medicine and Animal Sciences
Gunita Deksne
Gunita Deksne
Institute of Food Safety
United States
Lis Alban
Lis Alban
University of Copenhagen
Denmark
Maria Vang Johansen
Maria Vang Johansen
University of Copenhagen
Denmark

Parasite Epidemiol Control 2019 May 4;5:e00100. Epub 2019 Mar 4.

Laboratory of Parasitology, Department of Bacteria, Parasites & Fungi, Infectious Disease Preparedness, Statens Serum Institut, Artillerivej 5, 2300 Copenhagen S, Denmark.

Background: is an important foodborne zoonotic parasite. Meat of infected animals is presumed to constitute a major source of human infection and may be a driver of geographical variation in the prevalence of anti- antibodies in humans, which is substantial in the Nordic-Baltic region in northern Europe. However, data on seroprevalence of in different animal species used for human consumption are scattered.

Methods: We conducted a systematic review of seroprevalence studies and meta-analysis to estimate the seroprevalence of in five animal species that are raised or hunted for human consumption in the Nordic-Baltic region: domestic pigs (), sheep (), cattle (), wild boars (), and moose (). We searched for studies that were conducted between January 1990 and June 2018, and reported in articles, theses, conference abstracts and proceedings, and manuscripts. Subgroup analyses were performed to identify variables influencing the seroprevalence.

Findings: From a total of 271 studies identified in the systematic review, 32 were included in the meta-analysis. These comprised of 13 studies on domestic pigs, six on sheep, three on cattle, six on wild boars, and four on moose. The estimated pooled seroprevalence of was 6% in domestic pigs (CI: 3-10%), 23% in sheep (CI: 12-36%), 7% in cattle (CI: 1-21%), 33% in wild boars (CI: 26-41%), and 16% in moose (CI: 10-23%). High heterogeneity was observed in the seroprevalence data within each species. In all host species except wild boars, the pooled seroprevalence estimates were significantly higher in animals >1 year of age than in younger animals. Not all studies provided information on animal age, sensitivity and specificity of the serological method employed, and the cut-off values used for defining an animal seropositive.

Conclusions: A substantial proportion of animals raised or hunted for human consumption in the region had tested positive for . This indicates widespread exposure to among animals raised or hunted for human consumption in the region. Large variations were observed in the seroprevalence estimates between the studies in the region; however, studies were too few to identify spatial patterns at country-level.

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Source
http://dx.doi.org/10.1016/j.parepi.2019.e00100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411595PMC

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May 2019
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