Impact of osteoarthritis on activities of daily living: does joint site matter?

Aging Clin Exp Res 2019 Aug 21;31(8):1049-1056. Epub 2019 Mar 21.

MRC Lifecourse Epidemiology Unit, Southampton General Hospital, University of Southampton, Southampton, SO16 6YD, UK.

Background: We consider the relationships between a clinical and radiological diagnosis of knee or hip OA and activities of daily-living (ADL) in older adults.

Methods: Data were available for 222 men and 221 women from the Hertfordshire Cohort Study (HCS) who also participated in the UK component of the European Project on Osteoarthritis (EPOSA). Participants completed the EuroQoL survey where they reported if they had difficulties with mobility, self-care, usual activities and movement around their house. Hip and knee radiographs were graded for overall Kellgren and Lawrence score (positive definition defined as a 2 or above). Clinical OA was defined using American College of Rheumatology criteria.

Results: In men, a clinical diagnosis of hip or knee OA were both associated with reported difficulties in mobility, ability to self-care and performing usual-activities (hip OA: OR 17.6, 95% CI 2.07, 149, p = 0.009; OR 12.5, 95% CI 2.51, 62.3, p = 0.002; OR 4.92, 95% CI 1.06, 22.8, p = 0.042 respectively. Knee OA: OR 8.18, 95% CI 3.32, 20.2, p < 0.001; OR 4.29, 95% CI 1.34, 13.7, p = 0.014; OR 5.32, 95% CI 2.26, 12.5, p < 0.001 respectively). Similar relationships were seen in women, where in addition, a radiological diagnosis of knee OA was associated with difficulties performing usual activities (OR 3.25, 95% CI 1.61, 6.54, p = 0.001). In general, men with OA reported stronger associations between moving around the house, specifically around the kitchen (clinical hip OA: OR 13.7, 95% CI 2.20, 85.6, p = 0.005; clinical knee OA OR 8.45, 95% CI 1.97, 36.2, p = 0.004) than women.

Discussion And Conclusion: Clinical OA is strongly related to the ability to undertake ADL in older adults and should be considered in clinic consultations when seeing patients with OA.

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http://dx.doi.org/10.1007/s40520-019-01163-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661019PMC
August 2019
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References

(Supplied by CrossRef)

MJ Prince et al.
Lancet 2015

DT Felson et al.
Arthritis Rheum 1987

RC Lawrence et al.
Arthritis Rheum 2008

J Lord et al.
Health Technol Assess 1999

A Litwic et al.
Br Med Bull 2013

CW Hutton et al.
Ann Rheum Dis 1989

C Parsons et al.
SpringerPlus 2015

C Parsons et al.
Aging Clin Exp Res 2017

JH Kellgren et al.
Ann Rheum Dis 1957

SN Issa et al.
Curr Rheumatol reports 2006

M Marshall et al.
Nat Rev Rheumatol 2018

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