Splenic Marginal Zone B-Cell Lymphoma With Splenic Infarction in a Patient With Cold Agglutinin Disease.

Authors:
Ryusuke Nakamoto
Ryusuke Nakamoto
Tokyo University of Agriculture and Technology
Japan
Takahiko Utsumi
Takahiko Utsumi
Department of Haematology
Yoshihiro Yamamoto
Yoshihiro Yamamoto
Nagasaki University Graduate School of Biomedical Sciences
Japan

Clin Nucl Med 2019 05;44(5):e372-e374

Department of Pathology, Shiga General Hospital, Moriyama, Japan

We report a case of splenic marginal zone B-cell lymphoma discovered in a 73-year-old man with cold agglutinin disease. PET/CT revealed splenomegaly with focally intense uptake of F-FDG and diffusely increased bone marrow uptake, which was considered to be secondary to hemolytic anemia. Splenectomy was performed. The histopathology of the spleen showed splenic marginal zone B-cell lymphoma with partial splenic infarction, which correlated with the area of focal intense FDG uptake. Depending on the time since onset, splenic infarctions can present as focal FDG accumulation.

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Source
http://dx.doi.org/10.1097/RLU.0000000000002528DOI Listing
May 2019
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