Potential of the multivitamin-mineral-trace element composition LaVita® before, during and after pregnancy.

Neuro Endocrinol Lett 2019 Feb;39(7):501-514

International Society for Applied Preventive Medicine (I-GAP); and Health Campus, St. Elisabeth University of Health and Social Sciences (EU), Bratislava, Slovakia.

Objectives: Pregnancy is a period in life with a high demand of micronutrients. A prophylactic supplementation of folic acid to reduce the risk of neurological malformations in the newborn is common practice. The array of essential micronutrients during pregnancy includes neurotropic vitamins (Vitamin B6, B12 and folic acid), minerals like iron, and trace elements like zinc. As the serum level of most micronutritients is actively regulated by the organism, a prophylactic broad supplementation with a mild, but effective supplementation typically does not pose any risk for exaggerated serum levels, therefore prophylactic intake may be prefered to blood screening and specific interventions.

Methods: To investigate the ingredients' bioavailability of the complex vitamin-mineral-trace element composition LaVita® we recruited healthy volunteers for six months and observed the changes of pregnancy relevant parameters by means of laboratory measures. The study design was prospective, double blind, placebo controlled, and included a "male group control". We determined baseline parameters of folate, vitamin B6 and vitamin B12, iron, zinc, homocysteine and Hb-alpha-1c. After three and six months of daily intake of the study substance the blood tests were repeated and compared to the baseline levels.

Results: The regular intake resulted in an increase of the supplemented substances' serum levels. The metabolic parameter homocysteine decreased significantly, Hb-alpha-1c was slightly lowered.

Conclusion: The regular intake filled up the respective storage compartments and reservoirs in the tissues, and improved the metabolic status. Female participants tended to benefit more than male. We conclude that the composition is safe, and warrants optimized micronutrient supply during pregnancy or postnatal breastfeeding.

Download full-text PDF

Source
February 2019
3 Reads

Publication Analysis

Top Keywords

serum levels
8
element composition
8
vitamin b12
8
folic acid
8
regular intake
8
composition lavita®
8
pregnancy
5
controlled included
4
included "male
4
"male group
4
study design
4
placebo controlled
4
design prospective
4
group control"
4
double blind
4
blind placebo
4
prospective double
4
baseline parameters
4
b12 iron
4
iron zinc
4

Similar Publications