Successes and challenges for preventing measles, mumps and rubella by vaccination.

Authors:
Bettina Bankamp
Bettina Bankamp
Emory University
United States
Carole Hickman
Carole Hickman
University of California
United States
Joseph P Icenogle
Joseph P Icenogle
Mayo Clinic
United States
Paul A Rota
Paul A Rota
National Institute for Viral Disease Control and Prevention
China

Curr Opin Virol 2019 Feb 7;34:110-116. Epub 2019 Mar 7.

Viral Vaccine Preventable Diseases Branch, Division of Viral Diseases, National Center for Immunization and Respiratory Disease, Centers for Disease Control and Prevention, Atlanta, GA, 30329, USA. Electronic address:

The measles, mumps and rubella (MMR) vaccine has an outstanding safety record and is highly efficacious. High coverage with MMR has led to the elimination of endemic measles, rubella, and congenital rubella syndrome in the US. The biggest challenges to global measles and rubella control and elimination are insufficient vaccination coverage globally and increasing hesitancy. Despite high two dose coverage rates, mumps has made a resurgence in the US and other countries. Mumps outbreaks have occurred primarily in close contact, high-density settings and most cases had received a second dose 10 or more years previously. Waning humoral immunity and antigenic variation of circulating wild-type mumps strains may play a role in the mumps resurgence.

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S18796257183016
Publisher Site
http://dx.doi.org/10.1016/j.coviro.2019.01.002DOI Listing
February 2019
31 Reads

Article Mentions


Provided by Crossref Event Data
twitter
Twitter:
March 22, 2019, 8:54 pm EST

Publication Analysis

Top Keywords

mumps rubella
8
mumps resurgence
8
measles mumps
8
measles rubella
8
mumps
6
rubella
5
coverage rates
4
dose coverage
4
rates mumps
4
high dose
4
resurgence countries
4
mumps outbreaks
4
countries mumps
4
despite high
4
challenges global
4
increasing hesitancy
4
global measles
4
rubella control
4
elimination insufficient
4
insufficient vaccination
4

Similar Publications