J Ayurveda Integr Med 2019 Jan - Mar;10(1):69-71. Epub 2019 Mar 4.
Department of Maulika Siddhanta (Basic Principles of Ayurveda), Amrita School of Ayurveda, Amrita Vishwa Vidyapeetham, Amritapuri, India. Electronic address:
Med Hypotheses 2021 Sep 14;156:110679. Epub 2021 Sep 14.
School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab 144411, India. Electronic address:
Colon cancer is characterised by the persistent change in bowel habits due to the formation of polyps (cancerous) in the inner lining of the colon. Clinically, there are several anticancer drugs available to treat colon cancer. Oxaliplatin (third generation platinum drug) is widely prescribed anticancer drug due to its broad range anticancer properties and low toxicities over cisplatin and carboplatin. Read More
Am J Clin Nutr 2021 Sep 23. Epub 2021 Sep 23.
MRC/ARUK Centre for Musculoskeletal Ageing Research, National Institute for Health Research (NIHR), Nottingham Biomedical Research Centre, Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, NG7 2UH, UK.
Background: Evidence is emerging that inter-daily meal pattern variability potentially impacts on response such as thermic effect of food (TEF), macronutrient metabolism and appetite.Objectives: To investigate the effect of irregular meal pattern on TEF, glucose, insulin, lipid profile and appetite regulation in females with overweight or obesity and confirmed insulin resistance.Design: In a randomized crossover trial, 9 females [mean±SD BMI: 33. Read More
J Clin Child Adolesc Psychol 2021 Sep 23:1-14. Epub 2021 Sep 23.
School of Psychiatry, University of New South Wales.
Objective: The processes facilitating resilience are likely to be influenced by individual, familial and contextual factors that are dynamic across the life-course. These factors have been less studied in relation to resilience profiles evident in the developmental period between early to middle childhood, relative to later periods of adolescence or adulthood.Method: This study examined factors associated with in a cohort of 4,716 children known to child protection services by age 13 years, in the Australian State of New South Wales. Read More
Mol Pharm 2021 Sep 23. Epub 2021 Sep 23.
Department of Chemistry and Pharmacy, University of Sassari, 07100 Sassari, Italy.
Cutaneous melanoma is one of the most aggressive and metastatic forms of skin cancer. However, current therapeutic options present several limitations, and the annual death rate due to melanoma increases every year. Dermal delivery of nanomedicines can effectively eradicate primary melanoma lesions, avoid the metastatic process, and improve survival. Read More
Small 2021 Sep 23:e2101804. Epub 2021 Sep 23.
Beijing Advanced Innovation Center for Soft Matter Science and Engineering, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, 100029, P. R. China.
A cationic monofunctional platinum anticancer drug, phenanthriplatin (PhenPt(II)), exhibits promising anticancer effect on various cancer cell lines. Unlike the conventional platinum(II) drugs, PhenPt(II) is more likely to bind the N7 adenosine base of DNA in situ, and consequently resulting in a unique cellular response profile and unusual potency. However, since this drug is positively charged, it can easily bind to plasma protein that leads to rapid systematic clearance and deleterious toxicities, which greatly limits its in vivo application. Read More