Revival of favus in Japan caused by Trichophyton schoenleinii.

Authors:
Kentaro Iwasa
Kentaro Iwasa
The University of Tokyo
Japan
Kohei Ogawa
Kohei Ogawa
Kyoto University
Japan
Hiroaki Azukizawa
Hiroaki Azukizawa
Osaka University Graduate School of Medicine
Hiroshi Tanabe
Hiroshi Tanabe
Kanazawa Medical University
Japan
Tomoyuki Iwanaga
Tomoyuki Iwanaga
R&D Laboratories
Kazushi Anzawa
Kazushi Anzawa
Kanazawa Medical University
Japan
Takashi Mochizuki
Takashi Mochizuki
Kanazawa Medical University
Japan
Hideo Asada
Hideo Asada
Nara Medical University
Japan

J Dermatol 2019 Apr 15;46(4):347-350. Epub 2019 Feb 15.

Department of Dermatology, Nara Medical University, Kashihara, Japan.

Favus is a type of dermatophytosis known to produce yellow scutula around hair follicles. Most cases of this disease worldwide are infections of Trichophyton schoenleinii. Favus has rarely been reported in Japan throughout the last four decades, and T. schoenleinii has not been clinically isolated in any case during the period. Here, we report a case of favus of vellus hair observed in a 63-year-old Japanese woman. Fungal culture showed negative; however, we detected fungal elements in the crust and hair bulbs by Grocott staining. Pathogenic fungi were identified as T. schoenleinii by polymerase chain reaction-based DNA sequencing, targeting the internal transcribed spacer regions of the rRNA gene using the formalin-fixed, paraffin-embedded tissue sample. She was successfully treated with p.o. administration of terbinafine and topical application of luliconazole cream.

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http://dx.doi.org/10.1111/1346-8138.14804DOI Listing
April 2019
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