Multimodality treatment of head-and-neck soft-tissue sarcomas and short-term outcomes: Analysis from sarcoma medical oncology clinic.

Authors:
Ilavarasi Vanidassane, MBBS, MD, DM medical oncology
Ilavarasi Vanidassane, MBBS, MD, DM medical oncology
ALL INDIA INSTITUTE OF MEDICAL SCIENCES
DR
NEW DELHI, India | India
Dr  Sameer Rastogi, MD, DM Medical Oncology
Dr Sameer Rastogi, MD, DM Medical Oncology
All India Institute of Medical Sciences
Assistant Professor
Medical Oncology (Sarcoma)
Delhi | India

South Asian J Cancer 2019 Jan-Mar;8(1):69-71

Department of Medical Oncology, IRCH, AIIMS, New Delhi, India.

Background: Head-and-neck soft-tissue sarcomas (HNSTS) are extremely rare and lack definite guidelines.

Methods: We retrospectively analyzed consecutive adult patients with HNSTS who presented to our sarcoma medical oncology clinic from January 2016 to October 2017.

Results: There were a total of 30 patients. Unresectable localized disease was seen in 13 (43%) patients, metastatic disease 10 (34%) patients, while resectable disease in 7 (23%) patients only. Among unresectable localized disease, 3 (25%) patients could be converted to resectable disease after neoadjuvant therapy. Median follow period was 11 months. Progression-free survival was 19 months in patients with resectable disease and 6 months in patients with the unresectable/metastatic disease. Median OS was not reached.

Conclusion: Unresectable HNSTS has a poor outcome. Neoadjuvant therapy can be tried in selected cases for achieving respectability or for vital organ preservation until robust data are available. A multidisciplinary approach for local control is crucial in managing unresectable HNSTS.

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Source
http://dx.doi.org/10.4103/sajc.sajc_229_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348781PMC
February 2019
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