Clinical Heterogeneity in Cerebral Hemiatrophy Syndromes.

Mov Disord Clin Pract 2016 Jul-Aug;3(4):382-388. Epub 2016 Jan 18.

Department of Neurology Innsbruck Medical University Innsbruck Austria.

Background: Cerebral hemiatrophy syndromes can present with variable neurological symptoms. In childhood epilepsy, mental retardation and neuropsychiatric disorders are common while in adults movement disorders, such as highly asymmetric parkinsonism or hemidystonia as well as neuropsychiatric problems have been reported.

Methods: Here, we present three adult patients with features that expand the clinical spectrum and give an overview of the most common clinical signs associated with this rare condition.

Results: All three patients had prominent neuropsychiatric symptoms such as mood swings and increased irritability. Furthermore, one patient developed hemichorea which can be a rare presentation of cerebral hemiatrophy.

Conclusions: Cerebral hemiatrophy syndromes are a heterogeneous group of disorders that may also present with neuropsychiatric symptoms or hemichorea.

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Source
http://dx.doi.org/10.1002/mdc3.12301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353474PMC
January 2016
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