Ramsay Hunt syndrome with pontine lesion: A case report.

Authors:
Ye Ji
Ye Ji
Second Hospital of Hebei Medical University
China
Yi Zhang
Yi Zhang
Harvard Medical School
United States
Jin Li
Jin Li
Guangdong Medical University
United States
Dan-Dan Wu
Dan-Dan Wu
The First Affiliated Hospital of Wenzhou Medical College

Medicine (Baltimore) 2019 Feb;98(5):e14260

Department of Neurological Function Examination.

Rationale: The coexistence of Ramsay Hunt syndrome (RHS) and varicella-zoster virus (VZV) encephalitis is rare. A patient who developed RHS after being infected with VZV, along with a pontine lesion, is reported in the present study.

Patient Concerns: A 41-year-old male patient presented with his mouth askew for 7 days, and dizziness, accompanied by hearing loss for 3 days.

Diagnoses: The patient was initially diagnosed with RHS. Brainstem encephalitis was confirmed by lumbar puncture and cerebrospinal fluid. Brain magnetic resonance imaging (MRI) and diffusion-weighted imaging (DWI) revealed how VZV entered the intracranial space along the vestibulocochlear nerve and facial nerve in the acute period.

Interventions: Intravenous acyclovir, IV, immunoglobulins (IVIg) and methylprednisolone were administered.

Outcomes: The herpes was cleared up and left facial nerve palsy was improved, but hearing loss in the left ear did not improve.

Lessons: An MRI was necessary for some VZV infections limited to the cranial nerve, although there was no evidence of brain stem injury. DWI provided evidence, showing how VZV entered the brain in the early stage. This allowed the doctor to judge the necessity of a lumbar puncture.

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Source
http://dx.doi.org/10.1097/MD.0000000000014260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380842PMC
February 2019
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