Rare Association of Leukocytoclastic Vasculitis in Visceral Leishmaniaisis.

Authors:
Bharath A Chhabria
Bharath A Chhabria
Post Graduate Institute of Medical Education and Research
Chandigarh | India
Ram V Nampoothiri
Ram V Nampoothiri
Postgraduate Institute of Medical Education and Research
Chandigarh | India
Kirti Gupta
Kirti Gupta
Postgraduate Institute of Medical Education and Research
Chandigarh | India
Sanjay Jain
Sanjay Jain
Washington University School of Medicine
St. Louis | United States

Oman Med J 2019 Jan;34(1):66-69

Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

A 30-year-old man presented with fever, hepatosplenomegaly, and a rash over his lower limbs (palpable purpura). Evaluation revealed pancytopenia and hypergammaglobulinemia. A subsequent bone marrow examination and serology confirmed visceral leishmaniasis (kala-azar), while the biopsy of skin lesion suggested leukocytoclastic vasculitis. No alternate cause of vasculitis was forthcoming, and the patient was treated with conventional amphotericin B for 14 days after which resolution of symptoms (including the rash) was noted. Cutaneous vasculitis is an extremely rare complication following visceral leishmaniasis with no known cases reported thus far. Hence, a high index of suspicion is warranted in achieving timely diagnosis and initiation of appropriate therapy.

Download full-text PDF

Source
http://dx.doi.org/10.5001/omj.2019.11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330183PMC
January 2019
2 Reads

Publication Analysis

Top Keywords

visceral leishmaniasis
8
leukocytoclastic vasculitis
8
forthcoming patient
4
vasculitis forthcoming
4
alternate vasculitis
4
patient treated
4
days resolution
4
conventional amphotericin
4
treated conventional
4
vasculitis alternate
4
amphotericin days
4
lesion suggested
4
serology confirmed
4
examination serology
4
marrow examination
4
confirmed visceral
4
leishmaniasis kala-azar
4
resolution symptoms
4
skin lesion
4
kala-azar biopsy
4

Similar Publications