Pubfacts - Scientific Publication Data
  • Categories
  • |
  • Journals
  • |
  • Authors
  • Login
  • Categories
  • Journals

Search Our Scientific Publications & Authors

Publications
  • Publications
  • Authors
find publications by category +
Translate page:

Intra-articular ozone therapy efficiently attenuates pain in knee osteoarthritic subjects: A systematic review and meta-analysis.

Authors:
Ali Noori-Zadeh Salar Bakhtiyari Roghayeh Khooz Karimeh Haghani Shahram Darabi

Complement Ther Med 2019 Feb 28;42:240-247. Epub 2018 Nov 28.

Cellular and Molecular Research Center, Qazvin University of Medical Science, Qazvin, Iran.

Objectives: Ozone (O) gas is being used for chronic pain relief in knee osteoarthritis (KOA). However, there are controversies whether this gas can be medically useful in KOA pain treatments. The aim of this study was to evaluate the effectiveness of intra-articular ozone therapy for pain relief in KOA subjects using a systematic review and meta-analysis and standardized mean difference (SMD) as the effect size.

Method: Using specialized biomedical online databases of Pubmed Central, Pubmed, Medline, Google scholar, Scopus and Embase databases without the beginning date restriction until July 2018, the systematic review retrieved 10 studies for meta-analysis after fulfilling the inclusion and exclusion criteria.

Results: Analysis of Q and I% indices showed a high heterogeneity in the selected studies (2600.330 and 99.654, respectively), thus, the random-effects model was chosen for SMD calculation. The primary analysis for the main hypothesis found that the weighted pooled effect size for the impact of intra-articular ozone therapy for pain reduction was as follows: SMD= -28.551 (95% confidence interval, -32.553 to -24.549). The P-value for the significance of the combined SMD examined by the z-test was 0.000 and thus, it was clearly considered statistically significant.

Conclusion: This meta-analysis presents evidence that intra-articular ozone therapy is an effective way for chronic pain management in KOA.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ctim.2018.11.023DOI Listing
February 2019

Publication Analysis

Top Keywords

ozone therapy
16
intra-articular ozone
16
systematic review
12
subjects systematic
8
pain relief
8
chronic pain
8
therapy pain
8
review meta-analysis
8
pain
6
criteriaresults analysis
4
analysis indices
4
heterogeneity selected
4
indices high
4
high heterogeneity
4
studies 2600330
4
chosen smd
4
smd calculation
4
calculation primary
4
model chosen
4
random-effects model
4

Altmetric Statistics


Show full details
9 Total Shares
2 Facebook Pages
3 Tweets
2 Wikipedia Pages
7 Citations

Similar Publications

Integration of focal vibration and intra-articular oxygen-ozone therapy in rehabilitation of painful knee osteoarthritis.

Authors:
Teresa Paolucci Francesco Agostini Andrea Bernetti Marco Paoloni Massimiliano Mangone Valter Santilli Letizia Pezzi Rosa Grazia Bellomo Raoul Saggini

J Int Med Res 2021 Feb;49(2):300060520986705

Physical Medicine and Rehabilitation, Department of Medical, Oral and Biotechnological Sciences, G. d'Annunzio University of Chieti-Pescara, Chieti, Italy.

Objective: To examine the pain-reducing effects of intra-articular oxygen-ozone (OO) injections and mechanical focal vibration (mFV) versus OO injections alone in patients with knee osteoarthritis.

Methods: Patients with chronic pain (>6 weeks) due to knee osteoarthritis (II-III on the Kellgren-Lawrence scale) were consecutively enrolled and divided into two groups: OO (n = 25) and OO-mFV (n = 24). The visual analog scale (VAS), Knee Injury and Osteoarthritis Outcome Score (KOOS), and Medical Research Council (MRC) Manual Muscle Testing scale were administered at baseline (before treatment), after 3 weeks of treatment, and 1 month after the end of treatment. Read More

View Article and Full-Text PDF
February 2021
Similar Publications

The association between maternal exposure to outdoor air pollutants, inflammatory response, and birth weight in healthy women.

Authors:
Tai-Ho Hung Te-Yao Hsu Tao-Hsin Tung Ching-Chang Tsai Chia-Yu Ou Fen-Fang Chung Gwo-Hwa Wan

Environ Res 2021 Feb 24:110921. Epub 2021 Feb 24.

Department of Obstetrics and Gynecology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan; Department of Respiratory Therapy, College of Medicine, Chang Gung University, Taoyuan, Taiwan; Department of Respiratory Care, Chang Gung University of Science and Technology, Chiayi, Taiwan; Center for Environmental Sustainability and Human Health, Ming Chi University of Technology, Taishan, New Taipei, Taiwan. Electronic address:

Increased maternal inflammatory response has been noted in women with pregnancies complicated by preterm birth and small-for-gestational age infants. However, the association between gestational exposure to air pollutants, maternal inflammatory response, and fetal growth remains unclear. In this study, we aimed to investigate the association between exposure to air pollutants during pregnancy and the concentration of inflammatory indicators in maternal and fetal circulations, as well as fetal growth. Read More

View Article and Full-Text PDF
February 2021
Similar Publications

Ultrasound-guided periradicular oxygen-ozone injections as a treatment option for low back pain associated with sciatica.

Authors:
Cristiano Sconza Giacomo Braghetto Stefano Respizzi Emanuela Morenghi Elizaveta Kon Berardo Di Matteo

Int Orthop 2021 Feb 24. Epub 2021 Feb 24.

Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, 20090, Italy.

Background: The social impact and economic burden of low back pain are well known among the medical community. A novel therapeutic approach is represented by oxygen-ozone therapy, whose anti-inflammatory effects could be especially useful in patients with herniated discs. The most common administration is through a palpation-guided injection technique, although the use of ultrasound guidance could allow a more precise delivery of the therapeutic substance close to the nerve root. Read More

View Article and Full-Text PDF
February 2021
Similar Publications

Positive effects of COVID-19 lockdown on air quality of industrial cities (Ankleshwar and Vapi) of Western India.

Authors:
Ritwik Nigam Kanvi Pandya Alvarinho J Luis Raja Sengupta Mahender Kotha

Sci Rep 2021 02 19;11(1):4285. Epub 2021 Feb 19.

School of Earth, Ocean and Atmospheric Sciences (SEOAS), Goa University, Taleigao Plateau, Goa, 403206, India.

On January 30, 2020, India recorded its first COVID-19 positive case in Kerala, which was followed by a nationwide lockdown extended in four different phases from 25th March to 31st May, 2020, and an unlock period thereafter. The lockdown has led to colossal economic loss to India; however, it has come as a respite to the environment. Utilizing the air quality index (AQI) data recorded during this adverse time, the present study is undertaken to assess the impact of lockdown on the air quality of Ankleshwar and Vapi, Gujarat, India. Read More

View Article and Full-Text PDF
February 2021
Similar Publications

Association between lung function of school age children and short-term exposure to air pollution and pollen: the PARIS cohort.

Authors:
Hélène Amazouz Nicolas Bougas Michel Thibaudon Guillaume Lezmi Nicole Beydon Mélisande Bourgoin-Heck Jocelyne Just Isabelle Momas Fanny Rancière

Thorax 2021 Feb 16. Epub 2021 Feb 16.

CRESS, Inserm, INRAE, HERA Team, Université de Paris, Paris, France

Background: Daily levels of ambient air pollution and pollen may affect lung function but have rarely been studied together. We investigated short-term exposure to pollen and air pollution in relation to lung function in school-age children from a French population-based birth cohort.

Methods: This study included 1063 children from the PARIS (Pollution and Asthma Risk: an Infant Study) cohort whose lung function and FeNO measurements were performed at age 8 years old. Read More

View Article and Full-Text PDF
February 2021
Similar Publications
© 2021 PubFacts.
  • About PubFacts
  • Privacy Policy
  • Sitemap