Migration of the people and parasites: facts from survey of 5511 foreigners.

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Cas Lek Cesk 2018 Dec;157(7):373-379

In the course of the years 1983-1989, 5511 foreigners in the age of 20 to 40 years old from 87 countries were examined for human parasites. Everyone was examined within 1 months of arrival in the Czech Republic in the Active Case Detection (ACD) program. The intensity of infection was measured in those parasites which do not reproduce in the human body. Intensity of infection with geohelmints was express as a number of eggs per gram of feaces (EPG). 1079 foreigners infected with Trichuris trichiura are in 94,8 % suffering of light infection, the cohort of 694 foreigners infected with Ascaris lumbricoides suffered in 49,8 % of light infection, and 349 individuals infected with hookworms suffer in 96,0 % of cases of light infection. Pathology of infection with Schistosoma is founded on immunopathological reaction of the capillary endothelium to antigen excreted by mature eggs resulting in granulomatous inflammation with more than 20 times higher synthesis of collagen type I. Restructuralized tissue of liver, urinary bladder and large intestine with fibrotic scar, persisted 26 months though parasite was cured. 50 individuals from African countries were positive for infection with Plasmodium falciparum. 37/74, % of those were asymptomatic carriers with parasite load less than 10 000 merozoits per 1 µl of peripheric blood. That is the threshold between asymptomatic carrier and carries of the disease. All 37 Africans claimed absence of the disease before departure to the Czech Republic. The presence of RBC in trophozoit of Entamoeba histolytica is undoubtedly related to their virulence. In stool of 235 patients suffering for diarrhea in Cambodian hospital only 11,6 % of them harboured motile trophozoits of Entamoeba histolytica with phagocyte RBC confirming amoebic etiology of diarrhea. Such proportion of pathogenic amoeba is accepted all around the world. Keywords: Foreigners, imported parasites, active case detection, passive case detection, intensity of infection, clinical course of infection, cured parasite, persisting pathology.

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December 2018
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