Measurement of the serum levels of serum troponins I and T, albumin and C-Reactive protein in chronic hemodialysis patients and their relationship with left ventricular hypertrophy and heart failure.

Diabetes Metab Syndr 2019 Jan - Feb;13(1):522-525. Epub 2018 Nov 3.

Student Research Committee, Kurdistan University of Medical Sciences, Sanandaj, Iran. Electronic address:

Background: Hemodialysis patients are at high risk for cardiovascular diseases. The prognostic value of cardiac troponins, albumin and CRP in hemodialysis patients and their association with cardiac diseases has been proven. The aim of this study was to investigate the relationship between these factors and heart failure and left ventricular hypertrophy in hemodialysis patients in Sanandaj city.

Methods: A total of 90 hemodialysis patients referred to hemodialysis ward of Tohid Medical Center of Sanandaj were enrolled in the study. After receiving the required information from patients and recording them in questionnaire, blood samples were taken from them and were sen to Lab for Measurement. Finally, the data were analyzed using SPSS software and Spearman correlation coefficient for independent variables and Chi square test and correlation coefficient of Choprovert's for independent qualitative variable.

Results: In the case of LVH, 23.3% of patients were with normal thickness, 38.9% had mild LVH, 30% had moderate LVH and 7.8% had severe LVH. The mean serum albumin level in patients was 3.8 g/dl, CRP 9.4 mg/dL, and troponins I and T were 0.4 and 685.06 ng/dL, respectively. There was a statistically significant relationship between cardiac I and T troponins levels and CRP levels in patients with chronic hemodialysis (P < 0.05. There was a significant relationship between serum albumin level, troponins I, T and CRP with left ventricular hypertrophy in chronic hemodialysis patients (P < 0.05).

Conclusion: Serum levels of I and T troponins, albumin, as well as CRP, are related to heart failure and left ventricular hypertrophy in hemodialysis patients, and this can be used by physicians to determine the patient's ability and risk of disease Cardiovascular diseases.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.dsx.2018.11.029DOI Listing
April 2019
1 Read

Publication Analysis

Top Keywords

hemodialysis patients
20
patients
9
correlation coefficient
8
ventricular hypertrophy
8
chronic hemodialysis
8
troponins albumin
8
left ventricular
8
heart failure
8
cardiac troponins
8
hemodialysis
7
78% severe
4
samples sen
4
sen lab
4
required patients
4
patients recording
4
severe lvh
4
receiving required
4
lvh serum
4
recording questionnaire
4
serum albumin
4

Similar Publications